SCHEMBL8911423

SCHEMBL8911423

Cc1ccc(-c2ncnc(-c3ccc(OCCCCCCCCCCCCOc4ccc(-c5ncnc(-c6ccc(C)cc6C)n5)c(O)c4)cc3O)n2)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.37
NPC1 O15118 2/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PLK1 P53350 2/20 0.36
MAPK1 P28482 1/20 0.36
PDIA6 Q15084 1/20 0.36
PTPN11 Q06124 1/20 0.36
HTT P42858 1/20 0.35
MAOB P27338 2/20 0.35
ACACB O00763 1/20 0.35
ACACA Q13085 1/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
MAOA P21397 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29236180 0.95 NR5A1 (0.46) NR5A1NPC1MEN1ALDH1A1GAA
SCHEMBL3421399 0.95 NR5A1 (0.46) NR5A1NPC1MEN1ALDH1A1GAA
SCHEMBL29236170 0.94 NPC1 (0.44) NR5A1NPC1MEN1ALDH1A1GAA
SCHEMBL3728973 0.92 RARB (0.39) GAAPLK1MAPK1HRH3ADRB2
SCHEMBL1243194 0.91 ACACB (0.44) NPC1MEN1ALDH1A1GAAMAPT
SCHEMBL3225163 0.91 MAPK1 (0.40) NPC1MEN1GAAMAPTKMT2A
SCHEMBL7124098 0.90 PLK1 (0.35) NPC1MEN1ALDH1A1GAAMAPT
SCHEMBL3893045 0.89 NR5A1 (0.49) NR5A1NPC1MEN1ALDH1A1GAA
SCHEMBL6029292 0.89 NR5A1 (0.49) NR5A1NPC1MEN1ALDH1A1GAA
SCHEMBL22216823 0.89 NR5A1 (0.49) NR5A1NPC1MEN1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5597854-A PHOTOGRAPHIC APPLICATIONS, COATINGS, BINDERS, POLYMERS, TRIAZINE OR PYRIMIDINE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1997-01-28 US disclosed
EP-0711804-A2 Latent light stabilizers CIBA-GEIGY AG (CH) 1996-05-15 EP disclosed