SCHEMBL7124098

SCHEMBL7124098

Cc1ccc(-c2ncnc(-c3ccc(OCCCCCCOC(N)=O)cc3O)n2)c(C)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 3/20 0.35
PDIA6 Q15084 1/20 0.35
PTPN11 Q06124 2/20 0.35
PARP10 Q53GL7 2/20 0.34
MAOB P27338 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
GRM2 Q14416 1/20 0.33
F2 P00734 1/20 0.33
PLAU P00749 1/20 0.33
PRMT1 Q99873 1/20 0.33
ST14 Q9Y5Y6 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6551878 0.95 PDIA6 (0.37) PLK1PDIA6PTPN11PARP10MAOB
SCHEMBL8911423 0.90 NR5A1 (0.37) PLK1PDIA6PTPN11MAOBL3MBTL1
SCHEMBL3421399 0.86 NR5A1 (0.46) PLK1PTPN11L3MBTL1MEN1NPC1
SCHEMBL29236180 0.86 NR5A1 (0.46) PLK1PTPN11L3MBTL1MEN1NPC1
SCHEMBL29236170 0.84 NPC1 (0.44) PLK1PTPN11L3MBTL1HTTMEN1
SCHEMBL3728973 0.83 RARB (0.39) PLK1GAA
SCHEMBL1243194 0.82 ACACB (0.44) L3MBTL1HTTTDP1MEN1NPC1
SCHEMBL3225163 0.82 MAPK1 (0.40) MAOBHTTTDP1MEN1NPC1
SCHEMBL7117619 0.82 PLK1 (0.38) PLK1PTPN11MAOBHTTTDP1
SCHEMBL8385501 0.81 TSHR (0.40) PLK1PTPN11MAOBL3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030065066-A1 Triazine UV absorbers comprising amino resins JAKIELA DENNIS JOHN (US) 2003-04-03 US disclosed
EP-1090002-A1 AMINOPLAST ANCHORED TRISARYL-TRIAZINE UV ABSORBER Ciba SC Holding AG (CH) 2001-04-11 EP disclosed
WO-1999067246-A1 AMINOPLAST ANCHORED TRISARYL-TRIAZINE UV ABSORBER CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-12-29 WO disclosed