Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | USP14 | P54578 | 1/20 | 0.37 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.37 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571795 | 0.91 | MAPT (0.43) | ALDH1A1MAPTCYP4Z1PSMB5CYP4F2 | |
| SCHEMBL7388699 | 0.82 | CYP11B1 (0.43) | ALDH1A1MAPTPSMB5RORCPOLB | |
| SCHEMBL7394542 | 0.78 | CYP11B1 (0.40) | ALDH1A1MAPTPSMB5RORCPOLB | |
| SCHEMBL4506493 | 0.78 | CYP4F2 (0.66) | ALDH1A1MAPTCYP4Z1CYP4F2CYP4A11 | |
| SCHEMBL7396220 | 0.78 | RORC (0.42) | ALDH1A1MAPTRORCPOLBSMN1; SMN2 | |
| SCHEMBL8912089 | 0.77 | CYP11B1 (0.42) | ALDH1A1MAPTPSMB5RORCPOLB | |
| SCHEMBL8912114 | 0.77 | CYP11B1 (0.42) | ALDH1A1MAPTPSMB5RORCPOLB | |
| SCHEMBL7388224 | 0.74 | NPY1R (0.41) | MAPTPSMB5RORCPOLBSAE1 | |
| SCHEMBL7394134 | 0.74 | F2R (0.40) | MAPTPSMB5RORCPOLBLMNA | |
| SCHEMBL8910751 | 0.72 | PSMB5 (0.44) | ALDH1A1MAPTPSMB5RORCPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |