Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.74 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.68 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.68 |
| ▸ | FAAH | O00519 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.55 |
| ▸ | PRKCA | P17252 | 1/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.55 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.55 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.55 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002956 | 0.97 | DGKA (0.76) | DGKAFFAR1FFAR4FAAHKDM4E | |
| Glyceryl Monooleate SCHEMBL27768346 | 0.97 | DGKA (0.76) | DGKAFFAR1FFAR4FAAHKDM4E | |
| SCHEMBL2120988 | 0.94 | DGKA (0.83) | DGKAFFAR1FFAR4FAAHKDM4E | |
| SCHEMBL27520657 | 0.94 | DGKA (0.83) | DGKAFFAR1FFAR4FAAHKDM4E | |
| SCHEMBL15687 | 0.94 | DGKA (0.83) | DGKAFFAR1FFAR4FAAHKDM4E | |
| SCHEMBL2697011 | 0.94 | DGKA (0.83) | DGKAFFAR1FFAR4FAAHKDM4E | |
| Glycerol Monopalmitate SCHEMBL27539288 | 0.94 | DGKA (0.68) | DGKAFFAR1FFAR4FAAHKDM4E | |
| SCHEMBL28029821 | 0.93 | DGKA (0.81) | DGKAFFAR1FFAR4FAAHKDM4E | |
| Ethylene Glycol SCHEMBL28334748 | 0.92 | DGKA (0.79) | DGKAFFAR1FFAR4FAAHKDM4E | |
| Boric Acid SCHEMBL28465994 | 0.91 | DGKA (0.77) | DGKAFFAR1FFAR4FAAHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681876-A | DUSTLESS; CAPABLE OF BEING STIRRED INTO RESIN DISPERSION | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-10-28 | — | — | US | disclosed |