Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17494230 | 1.00 | GPR119 (0.52) | GPR119PPARGSYKCTSLSMN1; SMN2 | |
| SCHEMBL30400179 | 1.00 | GPR119 (0.52) | GPR119PPARGSYKCTSLSMN1; SMN2 | |
| SCHEMBL19195314 | 1.00 | GPR119 (0.52) | GPR119PPARGSYKCTSLSMN1; SMN2 | |
| SCHEMBL20329576 | 0.94 | GPR119 (0.54) | GPR119SYKCTSLSMN1; SMN2NPC1 | |
| SCHEMBL17946176 | 0.94 | GPR119 (0.54) | GPR119SYKCTSLSMN1; SMN2NPC1 | |
| SCHEMBL29286130 | 0.88 | GPR119 (0.48) | GPR119PPARGSYKCTSLSMN1; SMN2 | |
| SCHEMBL25245210 | 0.85 | GPR119 (0.59) | GPR119SYKSMN1; SMN2NPC1RAB9A | |
| SCHEMBL17591749 | 0.85 | GPR119 (0.59) | GPR119SYKSMN1; SMN2NPC1RAB9A | |
| SCHEMBL17591931 | 0.85 | PREP (0.53) | GPR119SYKCTSLMAPK1KMT2A | |
| SCHEMBL23576031 | 0.85 | PREP (0.53) | GPR119SYKCTSLMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380874-A | Pyrrolidine carbamates | DAIICHI SEIYAKU CO., LTD. (JP) | 1995-01-10 | — | — | US | claimed |
| JP-9143157-A | — | — | None | — | — | JP | disclosed |
| JP-H09143157-A | PYRROLIDINE DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1997-06-03 | — | — | JP | disclosed |
| US-5476950-A | Aminopyrrolidine compound | DAIICHI SEIYAKU CO., LTD. (JP) | 1995-12-19 | — | — | US | disclosed |
| US-5416222-A | Chemical intermediates to prepare pyridinocarboxylic acid derivatives with high antimicrobial activity and excellent pharmacokinetics | DAIICHI SEIYAKU CO., LTD. (JP) | 1995-05-16 | — | — | US | disclosed |
| US-5380874-A | Pyrrolidine carbamates | DAIICHI SEIYAKU CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| EP-0207420-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-05-06 | — | — | EP | disclosed |
| US-5098912-A | Bactericides for grampositive bacteria | DAIICHI SEIYAKU CO., LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0207420-A2 | Pyridonecarboxylic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1987-01-07 | — | — | EP | disclosed |