Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912137 | 1.00 | ATM (0.52) | ATMMEN1LMNAKMT2ACTSL | |
| SCHEMBL8913640 | 0.85 | ATM (0.56) | ATM | |
| SCHEMBL8913662 | 0.85 | ATM (0.56) | ATM | |
| SCHEMBL8911753 | 0.85 | ATM (0.56) | ATM | |
| SCHEMBL8911744 | 0.85 | ATM (0.56) | ATM | |
| SCHEMBL8912143 | 0.84 | ALDH1A1 (0.38) | — | |
| SCHEMBL8911942 | 0.84 | ATM (0.55) | ATM | |
| SCHEMBL8911934 | 0.84 | ATM (0.55) | ATM | |
| SCHEMBL8913834 | 0.82 | ATM (0.47) | ATM | |
| SCHEMBL8912049 | 0.82 | ATM (0.53) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799230-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019482-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1996-06-27 | — | — | WO | disclosed |