Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912301 | 1.00 | GAA (0.52) | GAAJAK2LMNAMAPTTLR8 | |
| SCHEMBL5649980 | 0.86 | TLR8 (0.54) | LMNATLR8MCHR1TSHRFFAR1 | |
| SCHEMBL10767910 | 0.84 | GAA (0.55) | GAAJAK2LMNAMAPTTSHR | |
| SCHEMBL79322 | 0.83 | GAA (0.53) | GAAJAK2LMNAMAPTTSHR | |
| SCHEMBL77820 | 0.82 | GAA (0.57) | GAAJAK2LMNAMAPTTLR8 | |
| SCHEMBL14181121 | 0.81 | LMNA (0.52) | GAAJAK2LMNAMAPTTSHR | |
| SCHEMBL29625318 | 0.81 | LMNA (0.57) | GAAJAK2LMNAMAPTTSHR | |
| SCHEMBL6698929 | 0.81 | LMNA (0.57) | GAAJAK2LMNAMAPTTSHR | |
| SCHEMBL10349822 | 0.81 | TLR8 (0.50) | LMNATLR8MCHR1TSHRFFAR1 | |
| SCHEMBL9521564 | 0.81 | GAA (0.56) | GAAJAK2LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35462-E | Silylated benzoic acid derivatives | CONSORTIUM FUR ELEKOCHEMISCHE IND. GMBH (DE) | 1997-02-25 | — | — | US | disclosed |
| EP-0325035-B1 | LIQUID CRYSTAL COMPOUND AND METHOD OF MANUFACTURING THE SAME, LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME AND LIQUID CRYSTAL DISPLAY DEVICE | KABUSHIKI KAISHA TOSHIBA (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-5106530-A | Liquid crystals | Consortium Fur Elektrochemische Ind. (DE) | 1992-04-21 | — | — | US | disclosed |
| US-4976887-A | Optically active liquid crystal compound and method of manufacturing the same, liquid crystal composition containing the same and liquid crystal display device | KABUSHIKI KAISHA TOSHIBA (JP) | 1990-12-11 | — | — | US | disclosed |