SCHEMBL891233

SCHEMBL891233

O=C(O)ON1CCCC1=O.[NaH]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
ALDH1A1 P00352 4/20 0.38
TSHR P16473 2/20 0.37
KMT2A Q03164 3/20 0.37
BRD4 O60885 1/20 0.37
BRD2 P25440 1/20 0.37
CYP1A2 P05177 2/20 0.34
CYP2D6 P10635 2/20 0.34
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 2/20 0.34
HPGD P15428 2/20 0.34
CYP3A4 P08684 1/20 0.34
BLM P54132 2/20 0.33
HTT P42858 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
RECQL P46063 1/20 0.33
CA12 O43570 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11037068 0.98 LMNA (0.41) LMNAALDH1A1TSHRKMT2ABRD4
SCHEMBL22749300 0.96 LMNA (0.39) LMNAALDH1A1TSHRKMT2ABRD4
SCHEMBL27364525 0.96 LMNA (0.39) LMNAALDH1A1TSHRKMT2ABRD4
SCHEMBL28078795 0.83 LMNA (0.42) LMNAALDH1A1TSHRKMT2ABRD4
SCHEMBL353225 0.83 LMNA (0.42) LMNAALDH1A1TSHRKMT2ABRD4
SCHEMBL27555930 0.82 BRD4 (0.40) LMNAALDH1A1TSHRKMT2ABRD4
SCHEMBL24783971 0.79 LMNA (0.39) LMNAALDH1A1TSHRKMT2ABRD4
SCHEMBL14693972 0.79 LMNA (0.39) LMNAALDH1A1TSHRKMT2ABRD4
SCHEMBL1291207 0.79 BRD4 (0.41) LMNAALDH1A1TSHRKMT2ABRD4
SCHEMBL28017585 0.79 LMNA (0.39) LMNAALDH1A1TSHRKMT2ABRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11298307-B2 Transparent or semitransparent cosmetic composition having enhanced amentoflavone stability AMOREPACIFIC CORPORATION (KR) 2022-04-12 US claimed
WO-2020245569-A1 SKIN TREATMENT COMPOSITION Boston Healthcare Limited (GB) 2020-12-10 WO claimed
US-20200054540-A1 TRANSPARENT OR SEMITRANSPARENT COSMETIC COMPOSITION HAVING ENHANCED AMENTOFLAVONE STABILITY AMOREPACIFIC CORPORATION (KR) 2020-02-20 US claimed
US-20180169002-A1 Skin Rejuvenation and Defense Systems and Methods CERBERUS BUSINESS FINANCE AGENCY, LLC, AS THE COLLATERAL AGENT 2018-06-21 US claimed
US-9925137-B2 Skin rejuvenation and defense system Maple Mountain Group, Inc. (US) 2018-03-27 US claimed
US-20170049692-A1 SKIN REJUVENATION AND DEFENSE SYSTEM CERBERUS BUSINESS FINANCE AGENCY, LLC, AS THE COLLATERAL AGENT 2017-02-23 US claimed
US-11298307-B2 Transparent or semitransparent cosmetic composition having enhanced amentoflavone stability AMOREPACIFIC CORPORATION (KR) 2022-04-12 US disclosed
US-20210022337-A1 Moisturizing Liquid Composition With Cationic Biocide Henkel IP & Holding GmbH (DE) 2021-01-28 US disclosed
WO-2020245569-A1 SKIN TREATMENT COMPOSITION Boston Healthcare Limited (GB) 2020-12-10 WO disclosed
US-20200054540-A1 TRANSPARENT OR SEMITRANSPARENT COSMETIC COMPOSITION HAVING ENHANCED AMENTOFLAVONE STABILITY AMOREPACIFIC CORPORATION (KR) 2020-02-20 US disclosed
CN-110475538-A Improve the transparent or semitransparent cosmetic composition of amentoflavone stability AMOREPACIFIC CORP 2019-11-19 CN disclosed
US-20190166829-A1 MOISTURIZING LIQUID COMPOSITION WITH CATIONIC BIOCIDE Henkel IP & Holding GmbH (DE) 2019-06-06 US disclosed
US-8802653-B2 Deodorant compositions C.B. FLEET COMPANY, INC. (US) 2014-08-12 US disclosed
US-20120083467-A1 DEODORANT COMPOSITIONS C. B. FLEET COMPANY, INCORPORATED 2012-04-05 US disclosed
US-4309447-A HYDROXYPROPYL-ETHERIFIED GLYCOLIPID ESTER KAO SOAP CO., LTD. (JP) 1982-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120083467-A1 DEODORANT COMPOSITIONS DDOST, DSC1, FUCA1 LMNA 717/4885ALDH1A1 738/4885TSHR 4479/4885
US-11298307-B2 Transparent or semitransparent cosmetic composition having enhanced amentoflavone stability TEAD2, FANCF, TEAD4 LMNA 1972/4885ALDH1A1 800/4885TSHR 3373/4885
US-20200054540-A1 TRANSPARENT OR SEMITRANSPARENT COSMETIC COMPOSITION HAVING ENHANCED AMENTOFLAVONE STABILITY TEAD2, FANCF, TEAD4 LMNA 1972/4885ALDH1A1 800/4885TSHR 3373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.