SCHEMBL8912586

SCHEMBL8912586

CCOc1ccc(N)cc1S(=O)(=O)O.CNc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.60
GAA P10253 4/20 0.51
MAPT P10636 4/20 0.51
KDM4E B2RXH2 3/20 0.51
TDP1 Q9NUW8 3/20 0.51
POLB P06746 3/20 0.51
ALDH1A1 P00352 3/20 0.51
RECQL P46063 2/20 0.51
CASP6 P55212 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
NSD2 O96028 1/20 0.51
APEX1 P27695 1/20 0.51
APOBEC3A P31941 1/20 0.51
APOBEC3G Q9HC16 1/20 0.51
CTDSP1 Q9GZU7 1/20 0.43
RAPGEF4 Q8WZA2 1/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
ELAVL1 Q15717 1/20 0.40
GNG2 P59768 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11654759 0.87 HSD17B10 (0.57) HSD17B10GAAMAPTKDM4ETDP1
SCHEMBL5677336 0.87 HSD17B10 (0.63) HSD17B10GAAMAPTKDM4ETDP1
SCHEMBL11653491 0.79 HSD17B10 (0.48) HSD17B10GAAMAPTKDM4ETDP1
SCHEMBL11655801 0.78 HSD17B10 (0.49) HSD17B10GAAMAPTKDM4ETDP1
SCHEMBL9360749 0.76 CYP19A1 (0.53) HSD17B10GAAMAPTKDM4ETDP1
SCHEMBL1606275 0.76 MAPT (0.57) HSD17B10GAAMAPTKDM4ETDP1
SCHEMBL11654660 0.75 HSD17B10 (0.54) HSD17B10GAAMAPTKDM4ETDP1
SCHEMBL157598 0.75 HSD17B10 (0.59) HSD17B10GAAMAPTKDM4ETDP1
SCHEMBL11284193 0.75 HSD17B10 (0.50) HSD17B10GAAMAPTKDM4ETDP1
SCHEMBL156095 0.74 HSD17B10 (0.49) HSD17B10GAAMAPTKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5596083-A CELLULOSE, POLYAMIDES, POLYURETHANES OR LEATHER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-01-21 US disclosed
EP-0719840-A1 Monoazo compounds and method for dyeing or printing fiber materials using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-07-03 EP disclosed