Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL344641 | 0.85 | ELANE (0.49) | CYP19A1GAAMAPTL3MBTL1TDP1 | |
| SCHEMBL344718 | 0.84 | ALOX5 (0.50) | MAOBMAOARAB9ASMN1; SMN2CA12 | |
| SCHEMBL1028419 | 0.81 | ALPG (0.51) | MAPTL3MBTL1TDP1LTA4HMAPK14 | |
| SCHEMBL5677336 | 0.78 | HSD17B10 (0.63) | HSD17B10GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL5659691 | 0.77 | MAOB (0.58) | CYP19A1GAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL8769337 | 0.77 | POLB (0.56) | HSD17B10GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL8164591 | 0.77 | HSD17B10 (0.45) | HSD17B10GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL9812902 | 0.77 | HSD17B10 (0.45) | HSD17B10GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL8912586 | 0.76 | HSD17B10 (0.60) | HSD17B10GAAMAPTL3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL11596441 | 0.76 | GAA (0.56) | CYP19A1GAAMAPTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356014-B1 | Reactive Dyes | ZENECA LTD (GB) | 1994-11-30 | — | — | EP | disclosed |
| US-5019134-A | Triphenodioxazines | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-28 | — | — | US | disclosed |
| EP-0356014-A1 | Reactive Dyes | ZENECA LIMITED (GB) | 1990-02-28 | — | — | EP | disclosed |