SCHEMBL8912876

SCHEMBL8912876

CCN(c1ccccc1)c1ccccc1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.40
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
NR3C2 P08235 1/20 0.40
HTR7 P34969 2/20 0.40
MAPK1 P28482 1/20 0.38
TSHR P16473 3/20 0.37
ALDH1A1 P00352 1/20 0.37
GLA P06280 1/20 0.37
HCN1 O60741 2/20 0.37
HCN4 Q9Y3Q4 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
KDM4C Q9H3R0 1/20 0.36
APAF1 O14727 1/20 0.36
CASP3 P42574 1/20 0.36
CASP6 P55212 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16577664 0.96 NR3C2 (0.40) MAPTCRHBPCRHR2NPSR1NR3C2
SCHEMBL24004252 0.93 MAPT (0.39) MAPTCRHBPCRHR2NPSR1NR3C2
SCHEMBL16577662 0.93 MAPT (0.39) MAPTCRHBPCRHR2NPSR1NR3C2
SCHEMBL23719332 0.90 HTR7 (0.39) MAPTHTR7MAPK1ALDH1A1SCN1A
SCHEMBL16577659 0.88 HTR7 (0.38) MAPTCRHBPCRHR2NPSR1NR3C2
SCHEMBL16577652 0.85 HTR7 (0.36) MAPTNPSR1NR3C2HTR7MAPK1
SCHEMBL16577708 0.84 HTR7 (0.38) HTR7MAPK1ALDH1A1DPP4PDCD1
SCHEMBL7149337 0.83 MAPT (0.47) MAPTCRHBPCRHR2NPSR1NR3C2
SCHEMBL16577704 0.82 HTR7 (0.37) HTR7MAPK1ALDH1A1DPP4PDCD1
SCHEMBL28443267 0.82 MEN1 (0.42) HTR7ALDH1A1CYP1A2ESR1DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5609970-A GENERATING ELECTROMAGNETIC RADIATION POLAROID CORPORATION (US) 1997-03-11 US claimed
US-20210305519-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-09-30 US disclosed
CN-102066390-A Composition for separating hydrogen STEPHAN CONSULTING CORP 2011-05-18 CN disclosed