Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CETP | P11597 | 3/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25862599 | 1.00 | L3MBTL1 (0.55) | L3MBTL1TDP1TSHRCETPNAAA | |
| SCHEMBL28286457 | 1.00 | L3MBTL1 (0.55) | L3MBTL1TDP1TSHRCETPNAAA | |
| SCHEMBL27189078 | 1.00 | L3MBTL1 (0.55) | L3MBTL1TDP1TSHRCETPNAAA | |
| SCHEMBL8263938 | 1.00 | L3MBTL1 (0.55) | L3MBTL1TDP1TSHRCETPNAAA | |
| SCHEMBL28427678 | 1.00 | L3MBTL1 (0.55) | L3MBTL1TDP1TSHRCETPNAAA | |
| SCHEMBL27365325 | 0.98 | L3MBTL1 (0.54) | L3MBTL1TDP1TSHRCETPNAAA | |
| SCHEMBL21696886 | 0.98 | L3MBTL1 (0.54) | L3MBTL1TDP1TSHRCETPNAAA | |
| SCHEMBL25862597 | 0.98 | L3MBTL1 (0.53) | L3MBTL1TDP1TSHRCETPNAAA | |
| SCHEMBL15887771 | 0.98 | L3MBTL1 (0.57) | L3MBTL1TDP1TSHRCETPNAAA | |
| SCHEMBL19227196 | 0.98 | L3MBTL1 (0.57) | L3MBTL1TDP1TSHRCETPNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614548-A | TREATING TUMORS AND HIV INFECTION, PROTEIN KINASE C INHIBITORS | WAKE FOREST UNIVERSITY (US) | 1997-03-25 | — | — | US | disclosed |
| WO-1990004918-A2 | QUATERNARY AMINE CONTAINING ETHER OR ESTER LIPID DERIVATIVES AND THERAPEUTIC COMPOSITIONS | WAKE FOREST UNIVERSITY (US) | 1990-05-17 | — | — | WO | disclosed |