SCHEMBL8912936

SCHEMBL8912936

N=C(N)CCCCCCCCCCCC(N)(N)C(=N)N

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SPHK2 Q9NRA0 1/20 0.48
SPHK1 Q9NYA1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3784331 0.77 SPHK2 (0.48) SPHK2SPHK1
SCHEMBL23668354 0.77 SPHK2 (0.72) SPHK2SPHK1
SCHEMBL31541186 0.77 SPHK2 (0.72) SPHK2SPHK1
SCHEMBL17747405 0.77 SPHK2 (0.72) SPHK2SPHK1
SCHEMBL31541184 0.77 SPHK2 (0.72) SPHK2SPHK1
SCHEMBL11154443 0.77 SPHK2 (0.72) SPHK2SPHK1
SCHEMBL7851689 0.74 SPHK2 (0.67) SPHK2SPHK1
SCHEMBL989053 0.72 SPHK2 (0.48) SPHK2SPHK1
SCHEMBL988370 0.72 SPHK2 (0.48) SPHK2SPHK1
SCHEMBL12341237 0.71 SPHK2 (0.52) SPHK2SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5654451-A GUANIDINE AND/OR NITROGUANIDINE-CONTAINING BIS/DI- OR TRIPEPTIDES/ COUPLED BY A DIAMINE; VIRICIDES; ANTIPROTOZOA AGENTS; FUNGICIDES; PARASITICIDES; DRUG DELIVERY; MEMBRANE TRANSPORTATION MAGAININ PHARMACEUTICALS INC. (US) 1997-08-05 US disclosed
EP-0679153-A4 AMINO ACIDS AND PEPTIDES HAVING MODIFIED TERMINALS. MAGAININ PHARMA (US) 1996-05-15 EP disclosed
EP-0679153-A1 AMINO ACIDS AND PEPTIDES HAVING MODIFIED TERMINALS MAGAININ PHARMACEUTICALS INC. (US) 1995-11-02 EP disclosed
WO-1994015909-A1 AMINO ACIDS AND PEPTIDES HAVING MODIFIED TERMINALS MAGAININ PHARMACEUTICALS, INC. (US) 1994-07-21 WO disclosed