Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12341240 | 0.92 | SPHK2 (0.48) | SPHK2SPHK1 | |
| SCHEMBL9135019 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL11760779 | 0.79 | SPHK2 (0.39) | SPHK2SPHK1ALDH1A1 | |
| SCHEMBL7851689 | 0.78 | SPHK2 (0.67) | SPHK2SPHK1 | |
| SCHEMBL9065 | 0.77 | KMT2A (0.40) | ALDH1A1 | |
| SCHEMBL989053 | 0.76 | SPHK2 (0.48) | SPHK2SPHK1 | |
| SCHEMBL988370 | 0.76 | SPHK2 (0.48) | SPHK2SPHK1 | |
| Guanidine SCHEMBL18009721 | 0.76 | TSHR (0.48) | ALDH1A1 | |
| SCHEMBL22271556 | 0.75 | SOAT1 (0.43) | ALDH1A1 | |
| SCHEMBL10722958 | 0.75 | SOAT1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943614-B2 | Cationic steroid antimicrobial diagnostic, detection, screening and imaging methods | BRIGHAM YOUNG UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-20180036217-A1 | MOUSSE-TYPE COSMETIC COMPOSITION CONTAINING SCORIA | AMOREPACIFIC CORPORATION (KR) | 2018-02-08 | — | — | US | disclosed |
| US-20170349544-A1 | Ethynylbenzene Derivatives | DUKE UNIVERSITY | 2017-12-07 | — | — | US | disclosed |
| US-9738604-B2 | Ethynylbenzene derivatives | DUKE UNIVERSITY (US) | 2017-08-22 | — | — | US | disclosed |
| US-9682970-B2 | Fluorescent compounds and uses thereof | BIOTIUM, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-06-30 | — | — | US | disclosed |
| US-20160024067-A1 | FLUORESCENT COMPOUNDS AND USES THEREOF | BIOTIUM, INC. | 2016-01-28 | — | — | US | disclosed |
| US-9221841-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2015-12-29 | — | — | US | disclosed |
| US-20150337003-A1 | ABIRATERONE AND ANALOGS THEREOF FOR THE TREATMENT OF DISEASES ASSOCIATED WITH CORTISOL OVERPRODUCTION | CORTENDO AB (PUBL) | 2015-11-26 | — | — | US | disclosed |
| US-20150191490-A1 | MITOTIC KINESIN INHIBTORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2015-07-09 | — | — | US | disclosed |
| US-20130034500-A1 | Cationic Steroid Antimicrobial Compositions and Methods of Use | SAVAGE PAUL B (US) | 2013-02-07 | — | — | US | disclosed |
| US-8324257-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-8268871-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-8211879-B2 | Cationic steroid antimicrobial compositions and methods of use | BRIGHAM YOUNG UNIVERSITY (US) | 2012-07-03 | — | — | US | disclosed |
| US-20110130327-A1 | Multi-Arm Amines and Uses Thereof | MARINA BIOTECH, INC. (US) | 2011-06-02 | — | — | US | disclosed |
| US-20110091376-A1 | CATATONIC STEROID ANTIMICROBIAL DIAGNOSTIC, DETECTION, SCREENING AND IMAGING METHODS | BRIGHAM YOUNG UNIVERSITY (US) | 2011-04-21 | — | — | US | disclosed |
| US-20100330086-A1 | CATIONIC STEROID ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-12-30 | — | — | US | disclosed |
| US-20100331283-A1 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-7795282-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2010-09-14 | — | — | US | disclosed |
| US-20100041719-A1 | MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191490-A1 | MITOTIC KINESIN INHIBTORS AND METHODS OF USE THEREOF | KIF5B, KIF2C, KIFC1 | SPHK2 1590/4885SPHK1 1846/4885ALDH1A1 2392/4885 |
| US-20100330086-A1 | CATIONIC STEROID ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE | CCL5, PRF1, NR3C1 | SPHK2 2747/4885SPHK1 1687/4885ALDH1A1 4393/4885 |
| US-20110130327-A1 | Multi-Arm Amines and Uses Thereof | SNRPE, SNRPA, ADAR | SPHK2 2598/4885SPHK1 2862/4885ALDH1A1 3803/4885 |
| US-20180036217-A1 | MOUSSE-TYPE COSMETIC COMPOSITION CONTAINING SCORIA | CUTA, MC1R, MSN | SPHK2 2977/4885SPHK1 2939/4885ALDH1A1 3383/4885 |
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | QPCT, PTMS, MAX | SPHK2 1033/4885SPHK1 514/4885ALDH1A1 4444/4885 |
| US-20130034500-A1 | Cationic Steroid Antimicrobial Compositions and Methods of Use | CCL5, PRF1, NR3C1 | SPHK2 2747/4885SPHK1 1687/4885ALDH1A1 4393/4885 |
| US-20150337003-A1 | ABIRATERONE AND ANALOGS THEREOF FOR THE TREATMENT OF DISEASES ASSOCIATED WITH CORTISOL OVERPRODUCTION | CYP46A1, CYP11B2, CYP11B1 | SPHK2 3142/4885SPHK1 3136/4885ALDH1A1 3763/4885 |
| US-20100041719-A1 | MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF | KIF5B, KIF2C, KIF18B | SPHK2 927/4885SPHK1 1019/4885ALDH1A1 2961/4885 |
| US-20110091376-A1 | CATATONIC STEROID ANTIMICROBIAL DIAGNOSTIC, DETECTION, SCREENING AND IMAGING METHODS | HSD17B13, S100A11, CYP2A13 | SPHK2 2266/4885SPHK1 1598/4885ALDH1A1 3121/4885 |
| US-20100331283-A1 | Mitotic kinesin inhibitors and methods of use thereof | KIF5B, KIF2C, KIFC1 | SPHK2 995/4885SPHK1 1081/4885ALDH1A1 2827/4885 |
| US-20170349544-A1 | Ethynylbenzene Derivatives | Q6ZSR9, EPX, ZYX | SPHK2 3826/4885SPHK1 3521/4885ALDH1A1 1651/4885 |
| US-20160024067-A1 | FLUORESCENT COMPOUNDS AND USES THEREOF | POLI, POLL, POLRMT | SPHK2 3522/4885SPHK1 3451/4885ALDH1A1 905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.