SCHEMBL8913073

SCHEMBL8913073

Cc1cc(C)cc(N)c1.Cc1ccc(N)cc1C

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.80
TSHR P16473 4/20 0.60
CASP1 P29466 4/20 0.54
CYP3A4 P08684 2/20 0.50
PDE10A Q9Y233 1/20 0.50
ACHE P22303 1/20 0.43
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
LMNA P02545 3/20 0.43
MAPT P10636 3/20 0.43
KDM4E B2RXH2 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
THRB P10828 2/20 0.43
ALOX15 P16050 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 2/20 0.43
TDP1 Q9NUW8 1/20 0.42
RECQL P46063 1/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33278 0.89
SCHEMBL29977912 0.89
Hydrochloric Acid SCHEMBL27923555 0.87 ALDH1A1 (0.94) ALDH1A1TSHRCASP1CYP3A4PDE10A
Methylamine SCHEMBL11811795 0.87 ALDH1A1 (0.94) ALDH1A1TSHRCASP1CYP3A4PDE10A
SCHEMBL11529106 0.87 ALDH1A1 (0.94) ALDH1A1TSHRCASP1CYP3A4PDE10A
Hydrochloric Acid SCHEMBL2868848 0.87 ALDH1A1 (0.94) ALDH1A1TSHRCASP1CYP3A4PDE10A
Ammonia Solution, Strong SCHEMBL28824371 0.87 ALDH1A1 (0.94) ALDH1A1TSHRCASP1CYP3A4PDE10A
Hydrochloric Acid SCHEMBL31458347 0.87 ALDH1A1 (0.94) ALDH1A1TSHRCASP1CYP3A4PDE10A
Cyanide SCHEMBL27784307 0.82 ALDH1A1 (0.84) ALDH1A1TSHRCASP1CYP3A4PDE10A
SCHEMBL9735305 0.78 ALDH1A1 (0.67) ALDH1A1TSHRCASP1CYP3A4PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5596083-A CELLULOSE, POLYAMIDES, POLYURETHANES OR LEATHER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-01-21 US disclosed
EP-0719840-A1 Monoazo compounds and method for dyeing or printing fiber materials using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-07-03 EP disclosed