Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913328 | 0.95 | MAPT (0.38) | MAPTPDE3BPDE3APDE4APDE4B | |
| SCHEMBL8912661 | 0.79 | PDE3B (0.38) | MAPTPDE3BPDE3APDE4APDE4B | |
| SCHEMBL8914142 | 0.78 | PDE3B (0.37) | MAPTPDE3BPDE3APDE4APDE4B | |
| SCHEMBL8911348 | 0.76 | PDE3B (0.39) | MAPTPDE3BPDE3APDE4APDE4B | |
| SCHEMBL8912147 | 0.76 | KDM4E (0.40) | MAPTPDE3BPDE3APDE4APDE4B | |
| SCHEMBL8291725 | 0.74 | PDE3B (0.41) | MAPTPDE3BPDE3APDE4APDE4B | |
| SCHEMBL8292411 | 0.74 | PDE3B (0.42) | MAPTPDE3BPDE3APDE4APDE4B | |
| SCHEMBL8298502 | 0.73 | PDE3B (0.38) | MAPTPDE3BPDE3APDE4APDE4B | |
| Bromide SCHEMBL8298175 | 0.73 | PDE3B (0.41) | MAPTPDE3BPDE3APDE4APDE4B | |
| SCHEMBL8291609 | 0.72 | PDE3B (0.37) | MAPTPDE3BPDE3APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605901-A | THERAPY FOR GRAM-NEGATIVE BACTERIA, NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1997-02-25 | — | — | US | claimed |
| EP-0661274-A1 | Indane derivatives, processes for preparing the same and synthetic intermediate of the same | TANABE SEIYAKU CO., LTD. (JP) | 1995-07-05 | — | — | EP | claimed |