Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.58 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | BACE1 | P56817 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913229 | 1.00 | MEN1 (0.62) | MEN1KMT2AAKR1C1NR4A1NR4A2 | |
| SCHEMBL14021666 | 0.85 | MEN1 (0.84) | MEN1KMT2AAKR1C1NR4A2SMN1; SMN2 | |
| SCHEMBL6955487 | 0.83 | NR1H4 (0.70) | NR4A1NR4A2NR4A3NR1H4NPC1 | |
| SCHEMBL13755053 | 0.83 | NR1H4 (0.62) | NR4A1NR4A2NR4A3NR1H4NPC1 | |
| SCHEMBL6539061 | 0.83 | MEN1 (0.60) | MEN1KMT2ANR4A1NR4A2NR4A3 | |
| SCHEMBL6539056 | 0.83 | MEN1 (0.60) | MEN1KMT2ANR4A1NR4A2NR4A3 | |
| SCHEMBL9432966 | 0.82 | MAOB (0.67) | NR4A1NR4A2NR4A3SMN1; SMN2MAPT | |
| SCHEMBL3662418 | 0.81 | NR1H4 (0.63) | NR4A1NR4A2NR4A3NR1H4NPC1 | |
| SCHEMBL3915887 | 0.81 | NR1H4 (0.59) | NR4A1NR4A2NR4A3NR1H4NPC1 | |
| SCHEMBL3915891 | 0.81 | NR1H4 (0.59) | NR4A1NR4A2NR4A3NR1H4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663207-A | ADMINISTERING TO INHIBIT DEVELOPMENT OF BREAST TUMOR | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-09-02 | — | — | US | disclosed |
| US-5397802-A | Gem-dichlorocyclopropanes as antitumor agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-03-14 | — | — | US | disclosed |