Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 17/20 | 0.46 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398546 | 0.93 | CCKBR (0.48) | CCKBR | |
| SCHEMBL9541664 | 0.89 | CCKBR (0.48) | CCKBR | |
| SCHEMBL8912603 | 0.89 | CCKBR (0.46) | CCKBRRAB9A | |
| SCHEMBL8398551 | 0.86 | CYP2C19 (0.41) | CCKBRAADAT | |
| SCHEMBL9544058 | 0.84 | CCKBR (0.47) | CCKBRAADAT | |
| SCHEMBL8401370 | 0.82 | CCKBR (0.48) | CCKBR | |
| SCHEMBL8402227 | 0.82 | CCKBR (0.46) | CCKBRAADATRAB9A | |
| SCHEMBL8402157 | 0.81 | CCKBR (0.50) | CCKBR | |
| SCHEMBL8402111 | 0.79 | CCKBR (0.65) | CCKBR | |
| SCHEMBL8398527 | 0.79 | CCKBR (0.48) | CCKBRAADATRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618811-A | Tetrahydro-1H-benzazepinones and hexahydroazepinones as selective cholecystokinin-B receptor antagonists | PFIZER INC. (US) | 1997-04-08 | — | — | US | disclosed |