Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.60 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913488 | 0.94 | TACR1 (0.56) | TACR1AGTR2 | |
| SCHEMBL8915024 | 0.94 | TACR1 (0.62) | TACR1AGTR2ALDH1A1 | |
| SCHEMBL8914615 | 0.91 | TACR1 (0.60) | TACR1AGTR2 | |
| SCHEMBL8914059 | 0.86 | TACR1 (0.61) | TACR1AGTR2 | |
| SCHEMBL8913484 | 0.86 | TACR1 (0.67) | TACR1AGTR2 | |
| SCHEMBL8913531 | 0.83 | TACR1 (0.82) | TACR1 | |
| SCHEMBL8915332 | 0.78 | TACR1 (0.84) | TACR1 | |
| SCHEMBL8915104 | 0.77 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8914640 | 0.71 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8914637 | 0.71 | TACR1 (1.00) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610165-A | N-acylpiperidine tachykinin antagonists | MERCK & CO., INC. (US) | 1997-03-11 | — | — | US | disclosed |
| WO-1995022525-A1 | N-ACYLPIPERIDINE TACHYKININ ANTAGONISTS | MERCK & CO., INC. (US) | 1995-08-24 | — | — | WO | disclosed |