SCHEMBL8915104

COC(=O)C1CCN(C(=O)N(c2ccccc2)c2ccccc2)C(C(=O)NCCN(C)Cc2ccccc2OC)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	TACR1	P25103	18/20	1.00

▸	KMT2A	Q03164	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8915880	0.94	TACR1 (0.89)	TACR1KMT2A
SCHEMBL8917231	0.94	TACR1 (0.88)	TACR1
SCHEMBL8913837	0.89	TACR1 (0.84)	TACR1
SCHEMBL8913852	0.89	TACR1 (0.84)	TACR1
SCHEMBL8913607	0.88	TACR1 (1.00)	TACR1
SCHEMBL8915177	0.85	TACR1 (1.00)	TACR1
SCHEMBL8915244	0.83	TACR1 (1.00)	TACR1
SCHEMBL7418622	0.79	TACR1 (1.00)	TACR1
SCHEMBL7416640	0.79	TACR1 (1.00)	TACR1
SCHEMBL8913490	0.77	TACR1 (0.60)	TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5610165-A	N-acylpiperidine tachykinin antagonists	MERCK & CO., INC. (US)	1997-03-11	—	—	US	disclosed