Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913518 | 1.00 | RARB (0.57) | RARBMMP2HDAC1HDAC2TP53 | |
| SCHEMBL8913373 | 0.95 | MMP2 (0.54) | RARBMMP2HDAC1HDAC2TP53 | |
| SCHEMBL5088870 | 0.87 | RARB (0.68) | RARBMMP2TP53TSHRALDH1A1 | |
| SCHEMBL8915721 | 0.82 | MAPT (0.53) | HDAC1HDAC2TP53TSHRALDH1A1 | |
| SCHEMBL8913234 | 0.82 | MAPT (0.53) | HDAC1HDAC2TP53TSHRALDH1A1 | |
| SCHEMBL8913516 | 0.81 | HDAC1 (0.49) | RARBMMP2HDAC1HDAC2MMP3 | |
| SCHEMBL8913735 | 0.81 | HDAC1 (0.49) | RARBMMP2HDAC1HDAC2MMP3 | |
| SCHEMBL8912717 | 0.81 | MAPT (0.55) | HDAC1HDAC2TP53TSHRALDH1A1 | |
| SCHEMBL3971811 | 0.80 | MMP2 (0.62) | RARBMMP2HDAC1HDAC2TP53 | |
| SCHEMBL8912214 | 0.80 | RARB (0.65) | RARBTP53TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35462-E | Silylated benzoic acid derivatives | CONSORTIUM FUR ELEKOCHEMISCHE IND. GMBH (DE) | 1997-02-25 | — | — | US | disclosed |
| US-5106530-A | Liquid crystals | Consortium Fur Elektrochemische Ind. (DE) | 1992-04-21 | — | — | US | disclosed |