Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10583564 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1GAASMN1; SMN2CA12 | |
| SCHEMBL30910416 | 0.84 | MMP3 (0.51) | KDM4EALDH1A1GAASMN1; SMN2CA12 | |
| SCHEMBL29538803 | 0.83 | CA12 (0.72) | KDM4EALDH1A1GAASMN1; SMN2CA12 | |
| SCHEMBL29544152 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1GAASMN1; SMN2CA12 | |
| SCHEMBL29350909 | 0.82 | MAP2K1 (0.56) | KDM4EALDH1A1GAASMN1; SMN2CA12 | |
| SCHEMBL29361704 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1GAASMN1; SMN2CA12 | |
| SCHEMBL29356663 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1GAASMN1; SMN2CA12 | |
| SCHEMBL29681151 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1GAASMN1; SMN2CA12 | |
| SCHEMBL30014703 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1GAASMN1; SMN2CA12 | |
| SCHEMBL24709906 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1GAASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627052-A | Methods for the production of proteins with a desired function | B.R. CENTRE, LTD. (CA) | 1997-05-06 | — | — | US | disclosed |
| EP-0542810-A1 | METHODS FOR THE PRODUCTION OF PROTEINS WITH A DESIRED FUNCTION | B.R. CENTRE LIMITED (CA) | 1993-05-26 | — | — | EP | disclosed |
| WO-1992002551-A1 | METHODS FOR THE PRODUCTION OF PROTEINS WITH A DESIRED FUNCTION | B.R. CENTRE LIMITED (CA) | 1992-02-20 | — | — | WO | disclosed |