Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.55 |
| ▸ | RRM1 | P23921 | 1/20 | 0.55 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.52 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.52 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 2/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17941639 | 0.89 | GRIA1 (0.57) | DPP7RRM1GRIA1 | |
| SCHEMBL17941640 | 0.89 | GRIA1 (0.57) | DPP7RRM1GRIA1 | |
| SCHEMBL29129460 | 0.87 | NAAA (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL8914221 | 0.87 | NAAA (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL8913994 | 0.87 | NAAA (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL12555472 | 0.87 | NAAA (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL3159222 | 0.87 | NAAA (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL8914559 | 0.87 | NAAA (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL17941646 | 0.87 | NAAA (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL17941645 | 0.87 | NAAA (0.59) | DPP7RRM1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654451-A | GUANIDINE AND/OR NITROGUANIDINE-CONTAINING BIS/DI- OR TRIPEPTIDES/ COUPLED BY A DIAMINE; VIRICIDES; ANTIPROTOZOA AGENTS; FUNGICIDES; PARASITICIDES; DRUG DELIVERY; MEMBRANE TRANSPORTATION | MAGAININ PHARMACEUTICALS INC. (US) | 1997-08-05 | — | — | US | disclosed |