Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 4/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | SELL | P14151 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914877 | 0.97 | PTGDR2 (0.44) | CYP19A1CYP11B1CYP11B2PTGDR2L3MBTL1 | |
| SCHEMBL8913569 | 0.94 | CYP19A1 (0.45) | CYP19A1CYP11B1CYP11B2PTGDR2L3MBTL1 | |
| SCHEMBL8914753 | 0.87 | KMT2A (0.49) | CYP19A1CYP11B1CYP11B2PTGDR2L3MBTL1 | |
| SCHEMBL6417850 | 0.85 | RARB (0.47) | CYP19A1CYP11B1CYP11B2PTGDR2MEN1 | |
| SCHEMBL6416735 | 0.84 | RARB (0.49) | CYP19A1CYP11B1CYP11B2PTGDR2MEN1 | |
| SCHEMBL8912688 | 0.82 | CYP19A1 (0.45) | CYP19A1CYP11B1CYP11B2PTGDR2KDM1A | |
| SCHEMBL8912832 | 0.82 | CYP19A1 (0.45) | CYP19A1CYP11B1CYP11B2PTGDR2KDM1A | |
| SCHEMBL8913874 | 0.81 | CYP11B1 (0.43) | CYP19A1CYP11B1CYP11B2PTGDR2KDM1A | |
| SCHEMBL8914817 | 0.79 | F2 (0.46) | L3MBTL1ALDH1A1 | |
| SCHEMBL8922934 | 0.77 | CYP19A1 (0.40) | CYP19A1CYP11B1CYP11B2PTGDR2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35462-E | Silylated benzoic acid derivatives | CONSORTIUM FUR ELEKOCHEMISCHE IND. GMBH (DE) | 1997-02-25 | — | — | US | disclosed |
| US-5277838-A | Silylated benzoic acid derivatives | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1994-01-11 | — | — | US | disclosed |
| US-5106530-A | Liquid crystals | Consortium Fur Elektrochemische Ind. (DE) | 1992-04-21 | — | — | US | disclosed |