Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 5/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913874 | 0.92 | CYP11B1 (0.43) | CYP19A1CYP11B1CYP11B2FAAHPTGDR2 | |
| SCHEMBL8912688 | 0.88 | CYP19A1 (0.45) | CYP19A1CYP11B1CYP11B2FAAHPTGDR2 | |
| SCHEMBL8912832 | 0.88 | CYP19A1 (0.45) | CYP19A1CYP11B1CYP11B2FAAHPTGDR2 | |
| SCHEMBL6416735 | 0.83 | RARB (0.49) | CYP19A1CYP11B1CYP11B2PTGDR2BCHE | |
| SCHEMBL6417850 | 0.82 | RARB (0.47) | CYP19A1CYP11B1CYP11B2PTGDR2BCHE | |
| SCHEMBL8914877 | 0.78 | PTGDR2 (0.44) | CYP19A1CYP11B1CYP11B2FAAHPTGDR2 | |
| SCHEMBL8913600 | 0.78 | RARB (0.48) | FAAHRARBMGLL | |
| SCHEMBL8912149 | 0.77 | F2 (0.44) | MGLL | |
| SCHEMBL8914352 | 0.77 | CYP19A1 (0.44) | CYP19A1CYP11B1CYP11B2FAAHPTGDR2 | |
| SCHEMBL16215324 | 0.76 | TSHR (0.56) | CYP19A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35462-E | Silylated benzoic acid derivatives | CONSORTIUM FUR ELEKOCHEMISCHE IND. GMBH (DE) | 1997-02-25 | — | — | US | disclosed |
| US-5277838-A | Silylated benzoic acid derivatives | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1994-01-11 | — | — | US | disclosed |
| US-5106530-A | Liquid crystals | Consortium Fur Elektrochemische Ind. (DE) | 1992-04-21 | — | — | US | disclosed |