SCHEMBL8914358

SCHEMBL8914358

O=C(c1ccccc1)C(CCl)(CCl)CCl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.52
MAPK1 P28482 3/20 0.52
ALDH1A1 P00352 2/20 0.52
GSK3B P49841 2/20 0.52
HIF1A Q16665 2/20 0.52
TRPA1 O75762 1/20 0.52
TDP1 Q9NUW8 4/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
CYP3A4 P08684 2/20 0.44
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CES2 O00748 3/20 0.44
TSHR P16473 2/20 0.44
DAO P14920 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
SRC P12931 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11529053 0.82 ALOX15 (0.43) CES1MAPK1ALDH1A1GSK3BHIF1A
SCHEMBL28436856 0.80 CES1 (0.50) CES1MAPK1ALDH1A1GSK3BHIF1A
SCHEMBL759482 0.80 CES1 (0.50) CES1MAPK1ALDH1A1GSK3BHIF1A
SCHEMBL11521626 0.79 CES1 (0.54) CES1MAPK1ALDH1A1GSK3BHIF1A
SCHEMBL10876359 0.78 CES1 (0.48) CES1MAPK1ALDH1A1GSK3BHIF1A
SCHEMBL3132247 0.78 CES1 (0.48) CES1MAPK1ALDH1A1GSK3BHIF1A
SCHEMBL1199961 0.77 CES1 (0.58) CES1MAPK1ALDH1A1GSK3BHIF1A
SCHEMBL5031584 0.77 CES1 (0.52) CES1MAPK1ALDH1A1GSK3BHIF1A
SCHEMBL7637171 0.77 SRC (0.47) CES1MAPK1ALDH1A1GSK3BHIF1A
Hydrochloric Acid SCHEMBL758628 0.77 CES1 (0.47) CES1MAPK1ALDH1A1GSK3BHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5607817-A DIALKYLAMINOPHENYL-SUBSTITUTED TRIAZINE SENSITIZER MITSUBISHI CHEMICAL CORPORATION (JP) 1997-03-04 US claimed
US-5607817-A DIALKYLAMINOPHENYL-SUBSTITUTED TRIAZINE SENSITIZER MITSUBISHI CHEMICAL CORPORATION (JP) 1997-03-04 US disclosed
EP-0537630-B1 Photopolymerizable composition MITSUBISHI CHEM CORP (JP) 1996-02-28 EP disclosed
EP-0300410-B1 Photopolymerizable composition MITSUBISHI CHEM IND (JP) 1994-10-26 EP disclosed
EP-0537630-A1 Photopolymerizable composition Mitsubishi Chemical Corporation (JP) 1993-04-21 EP disclosed
US-4966830-A Photopolymerizable composition MITSUBISHI KASEI CORPORATION (JP) 1990-10-30 US disclosed
EP-0300410-A2 Photopolymerizable composition Mitsubishi Chemical Corporation (JP) 1989-01-25 EP disclosed