Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.49 |
| ▸ | CTSL | P07711 | 8/20 | 0.46 |
| ▸ | CTSB | P07858 | 5/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPRB | P23467 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15686296 | 0.86 | CTSS (0.54) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL12385412 | 0.84 | CTSS (0.46) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL16449965 | 0.84 | CTSS (0.52) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL2297940 | 0.83 | MEN1 (0.46) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL19805060 | 0.82 | CTSS (0.51) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL15837157 | 0.82 | MEN1 (0.55) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL1150695 | 0.80 | CTSS (0.58) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL15837113 | 0.80 | CTSS (0.51) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL16450015 | 0.79 | CTSS (0.56) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL16449982 | 0.79 | MEN1 (0.52) | CTSSCTSLCTSBCTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625075-A | Metal radionuclide chelating compounds for improved chelation kinetics | NEORX CORPORATION (US) | 1997-04-29 | — | — | US | disclosed |
| US-5436352-A | Metal radionuclide chelating compounds for improved chelation kinetics | NEORX CORPORATION (US) | 1995-07-25 | — | — | US | disclosed |
| EP-0344724-B1 | METAL RADIONUCLIDE CHELATING COMPOUNDS FOR IMPROVED CHELATION KINETICS | NEORX CORPORATION (US) | 1993-08-11 | — | — | EP | disclosed |
| US-5075099-A | Metal radionuclide chelating compounds for improved chelation kinetics | NEORX CORPORATION (US) | 1991-12-24 | — | — | US | disclosed |
| US-4988496-A | Metal radionuclide chelating compounds for improved chelation kinetics | NEORX CORPORATION (US) | 1991-01-29 | — | — | US | disclosed |
| EP-0344724-A2 | Metal radionuclide chelating compounds for improved chelation kinetics | NEORX CORPORATION (US) | 1989-12-06 | — | — | EP | disclosed |