SCHEMBL8914751

SCHEMBL8914751

OCCOc1ccc(-n2nc3ccc(Cl)cc3n2)c(O)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.37
MEN1 O00255 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
MIF P14174 1/20 0.36
PDE2A O00408 3/20 0.36
PDE10A Q9Y233 3/20 0.36
PDE3B Q13370 1/20 0.36
PDE3A Q14432 1/20 0.36
P2RY12 Q9H244 1/20 0.36
MAPT P10636 2/20 0.35
TIPARP Q7Z3E1 1/20 0.34
CA12 O43570 1/20 0.34
CA9 Q16790 1/20 0.34
CYP2D6 P10635 1/20 0.34
HPGD P15428 1/20 0.34
DHODH Q02127 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17940503 0.89 PDE2A (0.41) KMT2AMEN1PDE2AMAPTDHODH
SCHEMBL9639345 0.89 DHODH (0.42) KMT2AMEN1PDE2AMAPTDHODH
SCHEMBL29492032 0.89 PDE2A (0.41) KMT2AMEN1PDE2AMAPTDHODH
SCHEMBL13700544 0.88 MIF (0.39) KMT2AMEN1CA1CA2CA4
SCHEMBL29492091 0.86 KMT2A (0.46) KMT2AMEN1MAPTKDM4ENPC1
SCHEMBL9639272 0.86 KMT2A (0.46) KMT2AMEN1MAPTKDM4ENPC1
SCHEMBL9747646 0.86 NR5A1 (0.45) PDE2A
SCHEMBL7787935 0.86 NR5A1 (0.45) PDE2A
SCHEMBL13370107 0.86 NR5A1 (0.45) PDE2A
SCHEMBL29492068 0.86 NR5A1 (0.45) PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5674670-A HAVING GOOD STABILITY, HIGH EXTINCTION COEFFICIENT, LITTLE OR NO YELLOW COLORATION EASTMAN KODAK COMPANY (US) 1997-10-07 US disclosed
EP-0750224-A2 2'-Hydroxyphenyl benzotriazole based UV absorbing polymers with particular substituents and photographic elements containing them EASTMAN KODAK COMPANY (US) 1996-12-27 EP disclosed