Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30518206 | 0.75 | KMT2A (0.52) | ABCG2ADORA3ADORA1ADORA2APOLB | |
| SCHEMBL14344519 | 0.75 | ABCG2 (0.43) | ABCG2ADORA3ADORA1ADORA2APOLB | |
| SCHEMBL28637477 | 0.75 | ADORA2A (0.53) | ABCG2ADORA3ADORA1ADORA2APOLB | |
| SCHEMBL10788916 | 0.75 | ABCG2 (0.42) | ABCG2ADORA3ADORA1ADORA2APOLB | |
| SCHEMBL10783317 | 0.75 | LMNA (0.47) | ABCG2ADORA3ADORA1ADORA2APOLB | |
| SCHEMBL28873874 | 0.75 | ABCG2 (0.42) | ABCG2ADORA3ADORA1ADORA2APOLB | |
| SCHEMBL2213565 | 0.75 | KMT2A (0.52) | ABCG2ADORA3ADORA1ADORA2APOLB | |
| SCHEMBL10783436 | 0.74 | MAPT (0.43) | ABCG2ADORA3ADORA1ADORA2APOLB | |
| SCHEMBL8914927 | 0.72 | HTT (0.38) | ADORA3ADORA1ADORA2APOLBL3MBTL1 | |
| SCHEMBL10785767 | 0.69 | KMT2A (0.52) | ABCG2POLBL3MBTL1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639753-A | CONTROLLING INSECTS IN AGRICULTURE CROPS | FMC CORPORATION (US) | 1997-06-17 | — | — | US | disclosed |
| US-5532367-A | LARVICIDES | FMC CORPORATION (US) | 1996-07-02 | — | — | US | disclosed |
| US-5521190-A | USEFUL AGAINST TOBACCO BUDWORM | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1994027439-A1 | INSECTICIDAL PTERIDINES AND 8-DEAZAPTERIDINES | FMC CORPORATION (US) | 1994-12-08 | — | — | WO | disclosed |