SCHEMBL8914942

SCHEMBL8914942

COc1cc(Oc2ccc(O)cc2)c(OC)cc1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.53
MAOB P27338 1/20 0.52
TUBB4A P04350 3/20 0.49
TUBB P07437 3/20 0.49
TUBA3C P0DPH7 3/20 0.49
TUBA1B P68363 3/20 0.49
TUBA4A P68366 3/20 0.49
TUBB4B P68371 3/20 0.49
TUBB3 Q13509 3/20 0.49
TUBB2A Q13885 3/20 0.49
TUBB8 Q3ZCM7 3/20 0.49
TUBA3E Q6PEY2 3/20 0.49
TUBA1A Q71U36 3/20 0.49
TUBA1C Q9BQE3 3/20 0.49
TUBB6 Q9BUF5 3/20 0.49
TUBB2B Q9BVA1 3/20 0.49
TUBB1 Q9H4B7 3/20 0.49
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
ESR2 Q92731 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9644251 0.81 LTA4H (0.63) LTA4HTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL9623896 0.81 LTA4H (0.57) LTA4HMAOBTUBB4ATUBBTUBA3C
SCHEMBL1402467 0.79 MAOB (0.54) MAOBMEN1KMT2AHTTALDH1A1
SCHEMBL9623668 0.79 MAOB (0.64) LTA4HMAOBTUBB4ATUBBTUBA3C
SCHEMBL1581477 0.78 MEN1 (0.56) LTA4HMEN1KMT2AESR2ESR1
SCHEMBL1170890 0.77 LTA4H (0.58) LTA4HMEN1KMT2AESR2ESR1
SCHEMBL20472303 0.75 LTA4H (0.50) LTA4HMAOBTUBB4ATUBBTUBA3C
SCHEMBL6830292 0.75 HTT (0.79) LTA4HMEN1KMT2AESR2ESR1
SCHEMBL69624 0.74 MAOB (0.59) MAOBMEN1KMT2AHTTALDH1A1
SCHEMBL13518328 0.74 TUBB1 (0.79) LTA4HMAOBTUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691442-A RADIATION TRANSPARENT POLYMERS WITH PHENOL ENDCAPPING THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1997-11-25 US disclosed
EP-0327634-B1 POLY(ARYL ETHER SULFONE) COMPOSITIONS HAVING IMPROVED FLOW PROPERTIES AMOCO CORPORATION (US) 1993-09-22 EP disclosed
US-5239043-A Reacting alkali metal double salt of dihydric phenol with dihalobenzenoid compound in prescence of cryptand AMOCO CORPORATION (US) 1993-08-24 US disclosed
US-5235020-A Process for preparation of poly(aryl ether) polymers by acyclic catalysts AMOCO CORPORATION (US) 1993-08-10 US disclosed
US-5235019-A Process for preparation of poly(aryl ether) polymers by macro monocyclic catalysts AMOCO CORPORATION (US) 1993-08-10 US disclosed
EP-0418377-A4 PROCESS FOR THE PREPARATION OF POLYCARBONATE AND/OR POLYARYLATE BLOCK COPOLYMERS WITH POLY(ARYL ETHERS) 1993-01-13 EP disclosed
EP-0176988-B1 AN ARTICLE MOLDED FROM A BLEND OF A POLY(ARYL ETHER KETONE)AND A POLY(ARYL ETHER SULFONE) AMOCO CORPORATION (US) 1992-12-02 EP disclosed
EP-0180042-B1 METAL PLATED POLY(ARYL ETHER) CONTAINING ARTICLES AMOCO CORPORATION (US) 1992-11-11 EP disclosed
US-5159028-A Coupling with diphenyl carbonate AMOCO CORPORATION (US) 1992-10-27 US disclosed
EP-0271701-B1 BINARY POLYCARBONATE BLENDS GENERAL ELECTRIC COMPANY (US) 1992-07-08 EP disclosed
EP-0033011-A1 Polyarylate blends with polyetherimides UNION CARBIDE CORPORATION (US) 1981-08-05 EP disclosed
US-4250279-A MOLDING MATERIALS UNION CARBIDE CORPORATION (US) 1981-02-10 US disclosed
US-4240974-A 1,2,3,4,9,9-HEXAHALO-1,4-DIHYDRO-1,4-METHANO-NAPHTHALENE-5,8 -DISULFONATE LITTLE JULIAN R (US) 1980-12-23 US disclosed
US-4208492-A ENGINEERING THERMOPLASTIC ELASTOMERS UNION CARBIDE CORPORATION (US) 1980-06-17 US disclosed
US-4175175-A POLYSULFONES, POLYSULFONAMIDES UNION CARBIDE CORPORATION (US) 1979-11-20 US disclosed
US-4174457-A Carbamate UNIROYAL, INC. (US) 1979-11-13 US disclosed
US-4108837-A THERMOPLASTIC, REACTING DIALKALI METAL SALT OF A DIHYDRIC PHENOL WITH A SUBSTITUTED DIHALOBENZENOID IN PRESENCE OF A SOLVENT UNION CARBIDE CORPORATION (US) 1978-08-22 US disclosed
US-4080408-A FIRE RETARDANTS UNIROYAL, INC. (US) 1978-03-21 US disclosed
US-4058568-A FIRE RETARDANT UNIROYAL, INC. (US) 1977-11-15 US disclosed
US-4009200-A FIREPROOFING POLYMERS UNIROYAL, INC. (US) 1977-02-22 US disclosed