Ethylbenzene

Ethylbenzene

SCHEMBL891495

CCc1ccccc1.Cc1cccc(C)c1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.67
ACHE P22303 2/20 0.57
TAAR1 Q96RJ0 1/20 0.48
IDO1 P14902 2/20 0.47
LMNA P02545 1/20 0.46
TSHR P16473 1/20 0.46
ALOX12 P18054 1/20 0.46
NPSR1 Q6W5P4 1/20 0.45
CYP1A2 P05177 3/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
MEN1 O00255 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
KMT2A Q03164 1/20 0.43
RAPGEF4 Q8WZA2 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
ALDH1A1 P00352 1/20 0.42
CTBP2 P56545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylbenzene SCHEMBL11134930 0.96 TP53 (0.61) TP53ACHETAAR1IDO1LMNA
Ethylbenzene SCHEMBL8077521 0.90 TP53 (0.74) TP53ACHETAAR1LMNATSHR
Ethylbenzene SCHEMBL17318272 0.90 TP53 (0.54) TP53ACHETAAR1IDO1LMNA
Ethylbenzene SCHEMBL2090159 0.90 TP53 (0.54) TP53ACHETAAR1IDO1LMNA
Ethylbenzene SCHEMBL28743490 0.90 TP53 (0.54) TP53ACHETAAR1IDO1LMNA
Ethylbenzene SCHEMBL27366576 0.90 TP53 (0.54) TP53ACHETAAR1IDO1LMNA
Ethylbenzene SCHEMBL9764715 0.87 TP53 (0.78) TP53ACHELMNATSHRALOX12
Ethylbenzene SCHEMBL598934 0.87 TP53 (0.78) TP53ACHELMNATSHRALOX12
Ethylbenzene SCHEMBL11049322 0.87 TP53 (0.78) TP53ACHELMNATSHRALOX12
Ethylbenzene SCHEMBL8927156 0.87 TP53 (0.78) TP53ACHELMNATSHRALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115616128-A Analytical method for separating and detecting intermediate xylene and paraxylene of ethylbenzene 江苏吴中医药集团有限公司 2023-01-17 CN claimed
US-5510562-A PRELIMINARY SEPARATION OF MIXTURE INTO P-XYLENE AND ETHYLBENZENE STREAM AND O- AND M-XYLENE STREAM, DISTILLATION ENICHEM S.P.A. (IT) 1996-04-23 US claimed
CN-115615888-A VOCs and PM2.5 combined source analysis method in atmospheric combined pollution 北京圣通和科技有限公司 2023-01-17 CN disclosed
EP-2108032-B1 UNLEADED FUEL COMPOSITIONS SHELL INT RESEARCH (NL) 2018-09-12 EP disclosed
CN-108046971-A Using mixed xylenes as raw material aromatics separation and the method for preparing M-phthalic acid 杭州多向流化学科技有限公司 2018-05-18 CN disclosed
US-9074153-B2 Unleaded fuel compositions SHELL OIL COMPANY (US) 2015-07-07 US disclosed
EP-2537913-A1 Unleaded fuel compositions Shell Internationale Research Maatschappij B.V. (NL) 2012-12-26 EP disclosed
US-20120279113-A1 UNLEADED FUEL COMPOSITIONS SHELL OIL COMPANY (US) 2012-11-08 US disclosed
US-20120080000-A1 UNLEADED FUEL COMPOSITIONS SHELL OIL COMPANY (US) 2012-04-05 US disclosed
EP-2108032-A1 UNLEADED FUEL COMPOSITIONS Shell Internationale Research Maatschappij B.V. (NL) 2009-10-14 EP disclosed
EP-1194236-B2 METAL-CONTAINING MACROSTRUCTURES OF POROUS INORGANIC OXIDE, PREPARATION THEREOF, AND USE EXXONMOBIL CHEM PATENTS INC (US) 2008-08-13 EP disclosed
US-20020170848-A1 Hydrocarbon conversion process and catalyst useful therein EXXONMOBIL CHEMICAL PATENTS INC. 2002-11-21 US disclosed
EP-1194236-A1 METAL-CONTAINING MACROSTRUCTURES OF POROUS INORGANIC OXIDE, PREPARATION THEREOF, AND USE ExxonMobil Chemical Patents Inc. (US) 2002-04-10 EP disclosed
WO-2000071255-A1 METAL-CONTAINING MACROSTRUCTURES OF POROUS INORGANIC OXIDE, PREPARATION THEREOF, AND USE EXXON CHEMICAL PATENTS INC. (US) 2000-11-30 WO disclosed
US-5948950-A Process for separating para-xylene, comprising an adsorption step with injection of water and a crystallization step INSTITUT FRANCAIS DU PETROLE (FR) 1999-09-07 US disclosed
US-4368347-A CHROMATOGRAPHY WITH POTASSIUM-EXCHANGED ZEOLITE SISAS S.P.A. (IT) 1983-01-11 US disclosed
US-4292142-A MIXTURE OF PHTHALIC ANHYDRIDE AND MALEIC ANHYDRIDE INTERNATIONAL SYNTHETIC RUBBER CO., LTD. (GB) 1981-09-29 US disclosed
US-4143084-A META AND PARA ETHYLTOLUENE AND DIETHYLBENZENE OBTAINED FROM DIRECT ETHYLATION OF TOLUENE AND BENZENE WITH NO SEPARATION MOBIL OIL CORPORATION (US) 1979-03-06 US disclosed
US-4120908-A XYLENES AND ETHYLBENZENE, MORDENITE CATALYST TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1978-10-17 US disclosed
US-4086287-A CRYSTALLINE ALUMINO-SILICATE ZEOLITE AS CATALYST MOBIL OIL CORPORATION (US) 1978-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020170848-A1 Hydrocarbon conversion process and catalyst useful therein SLC40A1, CD68, SLC39A3 TP53 3062/4885ACHE 3785/4885TAAR1 2431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.