Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.46 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1242235 | 0.85 | HTR2A (0.54) | BCL9CTNNB1HTR2AGAAPTPN7 | |
| SCHEMBL356806 | 0.85 | BCL9 (0.57) | BCL9CTNNB1HTR2AGAAKMT2A | |
| SCHEMBL356819 | 0.85 | BCL9 (0.50) | BCL9CTNNB1HTR2AGAAPTPN7 | |
| SCHEMBL29830631 | 0.82 | BCL9 (0.58) | BCL9CTNNB1HTR2AGAAKMT2A | |
| SCHEMBL30232724 | 0.82 | BCL9 (0.51) | BCL9CTNNB1HTR2AGAAKMT2A | |
| SCHEMBL29654784 | 0.80 | HTR2A (0.52) | BCL9CTNNB1HTR2AGAAKMT2A | |
| SCHEMBL26976971 | 0.80 | MGLL (0.56) | BCL9CTNNB1HTR2AGAAKMT2A | |
| SCHEMBL27108049 | 0.80 | BCL9 (0.56) | BCL9CTNNB1HTR2AGAAKMT2A | |
| SCHEMBL5712385 | 0.80 | BCL9 (0.51) | BCL9CTNNB1HTR2AGAAPTPN7 | |
| SCHEMBL27126 | 0.80 | HTR2A (0.54) | BCL9CTNNB1HTR2AGAAPTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684018-A | Acyloxyisopropyl carbamates as prodrugs for amine drugs | MERCK & CO., INC. (US) | 1997-11-04 | — | — | US | disclosed |
| WO-1996018605-A1 | ACYLOXYISOPROPYL CARBAMATES AS PRODRUGS FOR AMINE DRUGS | MERCK & CO., INC. (US) | 1996-06-20 | — | — | WO | disclosed |