Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26513499 | 0.80 | TSHR (0.52) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL28075454 | 0.80 | TSHR (0.52) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL23539727 | 0.80 | TSHR (0.52) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL28075368 | 0.80 | TSHR (0.52) | TSHRALDH1A1MAPTABCC4LMNA | |
| Ammonia Solution, Strong SCHEMBL3120827 | 0.78 | TSHR (0.50) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL2010651 | 0.77 | TSHR (0.48) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL11697159 | 0.76 | TSHR (0.48) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL9211258 | 0.76 | TSHR (0.48) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL9211215 | 0.76 | TSHR (0.48) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL18480166 | 0.76 | TSHR (0.48) | TSHRALDH1A1MAPTABCC4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120083575-A1 | COMB ARCHITECTURE OLEFIN BLOCK COPOLYMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-04-05 | — | — | US | claimed |
| US-7858707-B2 | Catalytic olefin block copolymers via polymerizable shuttling agent | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-12-28 | — | — | US | claimed |
| EP-2436703-B1 | Comb architecture olefin block copolymers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-04-25 | — | — | EP | disclosed |
| US-8907034-B2 | Comb architecture olefin block copolymers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-12-09 | — | — | US | disclosed |
| EP-1940896-B1 | CATALYTIC OLEFIN BLOCK COPOLYMERS VIA POLYMERIZABLE SHUTTLING AGENT | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-10-22 | — | — | EP | disclosed |
| US-8415434-B2 | Catalytic olefin block copolymers via polymerizable shuttling agent | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-04-09 | — | — | US | disclosed |
| US-20120083575-A1 | COMB ARCHITECTURE OLEFIN BLOCK COPOLYMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-04-05 | — | — | US | disclosed |
| US-20110092651-A1 | Catalytic Olefin Block Copolymers Via Polymerizable Shuttling Agent | ARRIOLA DANIEL J | 2011-04-21 | — | — | US | disclosed |
| US-7858707-B2 | Catalytic olefin block copolymers via polymerizable shuttling agent | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-12-28 | — | — | US | disclosed |
| US-20090163667-A1 | CATALYTIC OLEFIN BLOCK COPOLYMERS VIA POLYMERIZABLE SHUTTLING AGENT | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-06-25 | — | — | US | disclosed |
| EP-1940896-A1 | CATALYTIC OLEFIN BLOCK COPOLYMERS VIA POLYMERIZABLE SHUTTLING AGENT | Dow Global Technologies Inc. (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007035492-A1 | CATALYTIC OLEFIN BLOCK COPOLYMERS VIA POLYMERIZABLE SHUTTLING AGENT | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-03-29 | — | — | WO | disclosed |