SCHEMBL8915096

SCHEMBL8915096

C[Si](C)(c1ccc(Br)cc1)c1ccc(Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.50
ALDH1A1 P00352 5/20 0.45
HPGD P15428 2/20 0.44
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
ALOX15 P16050 2/20 0.38
MAPK1 P28482 2/20 0.38
NR1H2 P55055 1/20 0.35
NR1H3 Q13133 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
GAA P10253 2/20 0.34
IDO1 P14902 1/20 0.34
TSHR P16473 3/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
NOS1 P29475 1/20 0.33
DGAT1 O75907 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15485716 0.89 ESR1 (0.60) CYP2A6ALDH1A1HPGDESR1ESR2
SCHEMBL570229 0.81 CYP2A6 (0.50) CYP2A6ALDH1A1HPGDALOX15MAPK1
SCHEMBL8349228 0.79 CYP2A6 (0.47) CYP2A6ALDH1A1HPGDALOX15MAPK1
SCHEMBL9622511 0.77 CYP2A6 (0.44) CYP2A6ALDH1A1ALOX15MAPK1TDP1
SCHEMBL9754473 0.77 CYP2A6 (0.44) CYP2A6ALDH1A1HPGDALOX15MAPK1
SCHEMBL18692032 0.77 CYP2A6 (0.44) CYP2A6ALDH1A1ALOX15MAPK1GAA
SCHEMBL15679941 0.77 CYP2A6 (0.44) CYP2A6ALDH1A1HPGDALOX15MAPK1
SCHEMBL10617640 0.77 CYP2A6 (0.44) CYP2A6ALDH1A1HPGDALOX15MAPK1
SCHEMBL10317698 0.77 CYP2A6 (0.44) CYP2A6ALDH1A1HPGDALOX15MAPK1
SCHEMBL11751767 0.76 HPGD (0.55) ALDH1A1HPGDESR1ESR2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120199798-A Low-cost porous carbon core-shell nanosphere and preparation and application thereof 复旦大学 2025-06-24 CN claimed
CN-118222078-B Super-tough flame-retardant polycarbonate composite material and preparation method thereof 东莞港华高分子科技有限公司 2024-10-22 CN claimed
CN-118324800-A Novel phosphorus-silicon additive, high-temperature-resistant flame-retardant polycarbonate composite material and preparation method thereof 东莞港华高分子科技有限公司 2024-07-12 CN claimed
CN-118222078-A Super-tough flame-retardant polycarbonate composite material and preparation method thereof 东莞港华高分子科技有限公司 2024-06-21 CN claimed
CN-113629253-B Porous silicon@carbon core-shell nanosphere for lithium ion battery cathode and preparation and application thereof 复旦大学 2023-07-04 CN claimed
CN-113629253-A Porous silicon @ carbon core-shell nanosphere for lithium ion battery cathode and preparation and application thereof 复旦大学 2021-11-09 CN claimed
CN-120199798-A Low-cost porous carbon core-shell nanosphere and preparation and application thereof 复旦大学 2025-06-24 CN disclosed
CN-118222078-B Super-tough flame-retardant polycarbonate composite material and preparation method thereof 东莞港华高分子科技有限公司 2024-10-22 CN disclosed
CN-118324800-A Novel phosphorus-silicon additive, high-temperature-resistant flame-retardant polycarbonate composite material and preparation method thereof 东莞港华高分子科技有限公司 2024-07-12 CN disclosed
CN-118222078-A Super-tough flame-retardant polycarbonate composite material and preparation method thereof 东莞港华高分子科技有限公司 2024-06-21 CN disclosed
CN-117946612-A Packaging material composition, packaging structure and display device 杭州福斯特应用材料股份有限公司 2024-04-30 CN disclosed
CN-113629253-B Porous silicon@carbon core-shell nanosphere for lithium ion battery cathode and preparation and application thereof 复旦大学 2023-07-04 CN disclosed
CN-113629253-A Porous silicon @ carbon core-shell nanosphere for lithium ion battery cathode and preparation and application thereof 复旦大学 2021-11-09 CN disclosed
US-9287515-B2 Compositions comprising organic and organometallic compounds, and their applications in organic electroluminescence, light emission, display, and illumination devices UDC Ireland (IE) 2016-03-15 US disclosed
US-8513649-B2 Vinyl-based polymer with silicon or/and tin and organic light emission diode using the same CHEIL INDUSTRIES, INC. (KR) 2013-08-20 US disclosed
US-8513649-B2 Vinyl-based polymer with silicon or/and tin and organic light emission diode using the same CHEIL INDUSTRIES, INC. (KR) 2013-08-20 US disclosed
US-20120153272-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120153272-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20100237329-A1 VINYL-BASED POLYMER WITH SILICON OR/AND TIN AND ORGANIC LIGHT EMISSION DIODE USING CHEIL INDUSTRIES, INC. (KR) 2010-09-23 US disclosed
US-5679818-A Inorganic arylacetylenic monomers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1997-10-21 US disclosed