Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349228 | 0.97 | CYP2A6 (0.47) | CYP2A6ALDH1A1NR1H2NR1H3IDO1 | |
| SCHEMBL4874529 | 0.92 | ALDH1A1 (0.48) | CYP2A6ALDH1A1NR1H2NR1H3MAPK1 | |
| SCHEMBL15678827 | 0.85 | ALDH1A1 (0.42) | CYP2A6ALDH1A1MAPK1GAATSHR | |
| SCHEMBL19624747 | 0.85 | CYP2A6 (0.36) | CYP2A6ALDH1A1NR1H2NR1H3IDO1 | |
| SCHEMBL15906973 | 0.85 | CYP2A6 (0.36) | CYP2A6ALDH1A1NR1H2NR1H3IDO1 | |
| SCHEMBL586534 | 0.83 | NR1H2 (0.50) | NR1H2NR1H3GAAHPGD | |
| SCHEMBL11749536 | 0.82 | LMNA (0.59) | ALDH1A1MAPK1CA1CA2CES2 | |
| SCHEMBL8915096 | 0.81 | CYP2A6 (0.50) | CYP2A6ALDH1A1NR1H2NR1H3IDO1 | |
| SCHEMBL15906942 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPK1TDP1TSHRCES2 | |
| SCHEMBL9754473 | 0.77 | CYP2A6 (0.44) | CYP2A6ALDH1A1IDO1ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 458 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040632-A | Polydiphenylacetylene derivative capable of rapidly detecting nitrobenzene explosives, synthesis method and application thereof | 浙江大学绍兴研究院 | 2025-05-27 | — | — | CN | claimed |
| CN-119874533-A | Synthesis method of 3, 5-difluoro-4-amino-4' -iodobiphenyl | 联化昂健医药科技(上海)有限公司 | 2025-04-25 | — | — | CN | claimed |
| US-12428429-B2 | Amine compound and organic light-emitting diode including same | SFC CO., LTD. (KR) | 2025-09-30 | — | — | US | disclosed |
| CN-120040632-A | Polydiphenylacetylene derivative capable of rapidly detecting nitrobenzene explosives, synthesis method and application thereof | 浙江大学绍兴研究院 | 2025-05-27 | — | — | CN | disclosed |
| CN-119954646-A | Boron radical mediated nickel catalyzed C (sp3)-C(sp2) Cross coupling process | 合肥工业大学 | 2025-05-09 | — | — | CN | disclosed |
| CN-119874533-A | Synthesis method of 3, 5-difluoro-4-amino-4' -iodobiphenyl | 联化昂健医药科技(上海)有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-119874533-A | Synthesis method of 3, 5-difluoro-4-amino-4' -iodobiphenyl | 联化昂健医药科技(上海)有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-119822988-A | Photochemical synthesis method of formanilide compound | 合肥工业大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-115362151-B | Arylpiperidines as monoacylglycerol lipase modulators | 詹森药业有限公司 | 2025-02-11 | — | — | CN | disclosed |
| EP-4116297-B1 | CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING | SFC CO LTD (KR) | 2025-01-08 | — | — | EP | disclosed |
| EP-3654395-B9 | ORGANIC LIGHT EMITTING DIODE HAVING HIGH EFFICIENCY | SFC CO LTD (KR) | 2024-11-06 | — | — | EP | disclosed |
| WO-1996040681-A1 | N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1996-12-19 | — | — | WO | disclosed |
| EP-0742222-A2 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |
| EP-0722959-A2 | Highly oxygen-permeable heat-resistant material | Menicon Co., Ltd. (JP) | 1996-07-24 | — | — | EP | disclosed |
| US-5175243-A | Reaction of a sulfur source and a dihalobenzene in cyclic amide | PHILLIPS PETROLEUM COMPANY (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0486014-A1 | Process for preparing arylene sulfide polymers | PHILLIPS PETROLEUM COMPANY (US) | 1992-05-20 | — | — | EP | disclosed |
| US-5026894-A | Compound for use in the synthesis of semiconducting polymers with perpendicularly arranged cores and method of synthesizing said compound | UNIVERSITY OF SOUTH CAROLINA (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0403713-A1 | Novel acetylcholinesterase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4609651-A | ANTIGESTATION, ANTIMINERALOCORTICOID | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-09-02 | — | — | US | disclosed |
| EP-0147361-A2 | 11-Beta-aryl-estradienes, their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12428429-B2 | Amine compound and organic light-emitting diode including same | MAOA, AOC2, MAOB | CYP2A6 1843/4885ALDH1A1 93/4885NR1H2 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.