SCHEMBL8915285

SCHEMBL8915285

[CH2]OCCCC(=O)OCC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.57
DGKA P23743 1/20 0.47
GAA P10253 2/20 0.46
MGAM O43451 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
NR1I2 O75469 1/20 0.46
PGR P06401 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
PTGS2 P35354 1/20 0.46
PDE4D Q08499 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
RAB9A P51151 1/20 0.45
ALDH1A1 P00352 3/20 0.43
TSHR P16473 3/20 0.43
CYP3A4 P08684 1/20 0.43
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
TRPA1 O75762 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7361037 0.86
SCHEMBL907371 0.82 CYP1A2 (0.61) CYP1A2DGKAGAAMGAMSI
SCHEMBL50734 0.81 CYP1A2 (0.73) CYP1A2DGKAGAAMGAMSI
SCHEMBL50610 0.81 CYP1A2 (0.73) CYP1A2DGKAGAAMGAMSI
SCHEMBL1331978 0.81 CYP1A2 (0.73) CYP1A2DGKAGAAMGAMSI
SCHEMBL8570508 0.81 CYP1A2 (0.73) CYP1A2DGKAGAAMGAMSI
SCHEMBL2943131 0.80 CYP1A2 (0.59) CYP1A2DGKAGAAMGAMSI
SCHEMBL2607005 0.80 CYP1A2 (0.59) CYP1A2DGKAGAAMGAMSI
SCHEMBL10640143 0.80 CYP1A2 (0.59) CYP1A2DGKAGAAMGAMSI
SCHEMBL18256469 0.79 CYP1A2 (0.53) CYP1A2DGKAGAAMGAMSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5616581-A BACTERICIDES YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1997-04-01 US disclosed
US-5504082-A BACTERICIDE FOR HELICOBACTER, ANTIULCER AGENT, GASTRIC ACIDSUPPRESSOR YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1996-04-02 US disclosed
EP-0644191-A1 PYRIDINE COMPOUND AND MEDICINAL USE THEREOF YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1995-03-22 EP disclosed