Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15478668 | 0.94 | DGKA (0.55) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL17909510 | 0.94 | CYP1A2 (0.55) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL17908617 | 0.94 | CYP1A2 (0.55) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL17908601 | 0.94 | CYP1A2 (0.55) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL8430494 | 0.94 | CYP1A2 (0.55) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL2943131 | 0.93 | CYP1A2 (0.59) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL17909089 | 0.92 | DGKA (0.53) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL17909038 | 0.92 | DGKA (0.53) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL17908715 | 0.92 | DGKA (0.53) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL19666668 | 0.92 | CYP1A2 (0.53) | CYP1A2GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110507670-B | Refined bear gall powder and application of refined bear gall powder in preventing and treating liver diseases, liver fibrosis and improving liver function | 江西天元药业有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-112834649-A | Method for measuring residual quantity of chloramphenicol drugs in animal derived food | 镇江华大检测有限公司 | 2021-05-25 | — | — | CN | claimed |
| CN-110511261-B | Refined bear gall powder with improved bioavailability and preparation method thereof | 江西天元药业有限公司 | 2021-05-11 | — | — | CN | claimed |
| CN-110511261-A | The refined bear gall powder and its preparation method that bioavilability improves | JIANGXI TIANYUAN MEDICINE CO LTD | 2019-11-29 | — | — | CN | claimed |
| CN-110507670-A | Refined bear gall powder and prophylactic treatment hepatopathy liver fibrosis improve the purposes of liver function | JIANGXI TIANYUAN MEDICINE CO LTD | 2019-11-29 | — | — | CN | claimed |
| CN-110507669-A | Refined bear gall powder and its treatment cholecystitis gallstones disease improve the purposes of gallbladder function | JIANGXI TIANYUAN MEDICINE CO LTD | 2019-11-29 | — | — | CN | claimed |
| CN-108299361-A | A kind of method and application in preparation of anti-tumor drugs preparing five lactone E using Kadsura heteroclita as raw material | 湖南中医药大学 | 2018-07-20 | — | — | CN | claimed |
| CN-105646496-B | A kind of 7H- pyrrolo-es [2,3-d] pyrimidine derivatives, its synthetic method and application | 华侨大学 | 2018-07-20 | — | — | CN | claimed |
| CN-106018578-B | A kind of method of Ca-EDTA sodium content in measurement drug | 李宏 | 2018-07-13 | — | — | CN | claimed |
| CN-106018578-A | Method for measuring content of sodium calcium edetate in medicine | 李宏 | 2016-10-12 | — | — | CN | claimed |
| CN-105646496-A | 7H-pyrrolo[2,3-d] pyrimidine derivative and synthesis method and application thereof | 华侨大学 | 2016-06-08 | — | — | CN | claimed |
| CN-103554093-B | Tiagabine ethyl ester hydrochloride and preparation method thereof | SICHUAN CREDIT CHEMWERTH PHARMACEUTICAL CO.,LTD. (CN) | 2015-10-21 | — | — | CN | claimed |
| US-20240182463-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO., LTD. (JP) | 2024-06-06 | — | — | US | disclosed |
| CN-115015428-A | Detection method of polyphenol compounds in yellow wine | 绍兴市食品药品检验研究院 | 2022-09-06 | — | — | CN | disclosed |
| CN-112834649-A | Method for measuring residual quantity of chloramphenicol drugs in animal derived food | 镇江华大检测有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-111057122-B | Preparation method of rocuronium bromide | 武汉华龙生物制药有限公司 | 2021-04-30 | — | — | CN | disclosed |
| US-4005110-A | 2H-Cyclopenta(b)furan-2-ones | HOFFMANN-LA ROCHE INC. (US) | 1977-01-25 | — | — | US | disclosed |
| US-4001281-A | 2-Oxo-cyclopenta[b]furan-5α-carboxylic acid esters | HOFFMANN-LA ROCHE INC. (US) | 1977-01-04 | — | — | US | disclosed |
| US-3950348-A | INTERMEDIATE FOR PEPTIDES | MERCK & CO., INC. (US) | 1976-04-13 | — | — | US | disclosed |
| US-3944675-A | Substituted aryl and aralkyl amides in the treatment of parkinsonism | SCHERING CORPORATION (US) | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240182463-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | PREP, UNG, DPP4 | CYP1A2 1182/4885GAA 1254/4885MGAM 1649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.