Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835655 | 0.78 | CA12 (0.53) | CA2CA12CA1CA9SMN1; SMN2 | |
| SCHEMBL20169531 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHRKMT2AKDM4EGAA | |
| SCHEMBL6901552 | 0.74 | SMN1; SMN2 (0.60) | SMN1; SMN2TSHRKDM4EGAAALDH1A1 | |
| SCHEMBL5807041 | 0.74 | SMN1; SMN2 (0.60) | SMN1; SMN2TSHRKMT2AKDM4EGAA | |
| SCHEMBL7174025 | 0.73 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHRKMT2AKDM4EGAA | |
| SCHEMBL11437661 | 0.73 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHRKMT2AKDM4EGAA | |
| SCHEMBL6382412 | 0.73 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHRKMT2AKDM4EGAA | |
| SCHEMBL4700005 | 0.72 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRKMT2AKDM4EGAA | |
| SCHEMBL4354509 | 0.72 | SMN1; SMN2 (0.55) | SMN1; SMN2TSHRKMT2AKDM4EGAA | |
| SCHEMBL2635519 | 0.72 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRKMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691335-A | CARDIOVASCULAR DISORDERS | SUNTORY LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0721944-A1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LIMITED (JP) | 1996-07-17 | — | — | EP | disclosed |