Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915421 | 1.00 | THRB (0.50) | THRBATMTBXAS1HTTKMT2A | |
| SCHEMBL7799631 | 0.91 | HTT (0.44) | THRBATMTBXAS1HTTKMT2A | |
| SCHEMBL7799626 | 0.91 | HTT (0.44) | THRBATMTBXAS1HTTKMT2A | |
| SCHEMBL8917259 | 0.87 | HTT (0.46) | HTTKMT2ASMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL8917835 | 0.87 | HTT (0.46) | HTTKMT2ASMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL8962281 | 0.87 | HTT (0.46) | HTTKMT2ASMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL8917265 | 0.87 | HTT (0.46) | HTTKMT2ASMN1; SMN2HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL8422744 | 0.86 | HTT (0.45) | TBXAS1HTTKMT2ASMN1; SMN2HDAC3 | |
| SCHEMBL8962277 | 0.83 | CA12 (0.55) | HTTKMT2ASMN1; SMN2CA12CA1 | |
| SCHEMBL8962278 | 0.83 | CA12 (0.55) | HTTKMT2ASMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8225507-A | — | — | None | — | — | JP | disclosed |
| US-5663410-A | Cis-4-(2,2,3,3-tetrafluoropropoxy)-cinnamonitrile and trans-4-(2,2,3,3-tetrafluoropropoxy)-cinnamonitrile and a process for their preparation | HOECHST AKTIENGESELLSCHAFT | 1997-09-02 | — | — | US | disclosed |
| JP-H08225507-A | CIS-4-(2,2,3,3-TETRAFLUOROPROPOXY)CINNAMONITRILE AND TRANS-4(2,2,3,3-TETRAFLUOROPROPOXY)CINNAMONITRILE AND THEIR PRODUCTION | HOECHST AG | 1996-09-03 | — | — | JP | disclosed |
| EP-0711752-A2 | Cis-4-(2,2,3,3-tetrafluoropropoxy)cinnamic acid nitrile and trans-4-(2,2,3,3-tetrafluoro)cinnamic acid nitrile and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-15 | — | — | EP | disclosed |
| EP-0472392-A2 | Optically active triazole derivatives and compositions | ZENECA LIMITED (GB) | 1992-02-26 | — | — | EP | disclosed |