Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 6/20 | 0.79 |
| ▸ | PRKCG | P05129 | 5/20 | 0.78 |
| ▸ | PRKCB | P05771 | 5/20 | 0.78 |
| ▸ | PRKCH | P24723 | 5/20 | 0.78 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.78 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.78 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.78 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.78 |
| ▸ | PRKCI | P41743 | 4/20 | 0.78 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.78 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.78 |
| ▸ | USP2 | O75604 | 2/20 | 0.78 |
| ▸ | TP53 | P04637 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353576 | 0.92 | PRKCA (0.94) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL295345 | 0.92 | PRKCA (0.94) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL3211990 | 0.92 | PRKCA (0.94) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL1568997 | 0.92 | PRKCA (0.94) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL29706042 | 0.92 | PRKCA (0.94) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL8365006 | 0.91 | PRKCA (0.73) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL18399995 | 0.91 | PRKCA (0.95) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL2411275 | 0.91 | PRKCA (0.95) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL1954021 | 0.90 | PRKCA (0.65) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL3708285 | 0.88 | PRKCA (0.85) | PRKCAPRKCGPRKCBPRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663157-A | 22-en-25-oxa derivatives in the vitamin D series, process for their production, pharmaceutical preparations containing these derivatives as well as their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-09-02 | — | — | US | disclosed |
| US-5532228-A | ANTITUMOR, PSORIASIS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-07-02 | — | — | US | disclosed |