⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2158686 | 0.80 | SLC1A1 (0.37) | — | |
| SCHEMBL28322819 | 0.79 | — | — | |
| SCHEMBL28051778 | 0.79 | TSHR (0.39) | — | |
| SCHEMBL13462288 | 0.79 | — | — | |
| SCHEMBL366162 | 0.79 | — | — | |
| SCHEMBL818996 | 0.79 | — | — | |
| SCHEMBL28437975 | 0.79 | — | — | |
| SCHEMBL5904020 | 0.79 | — | — | |
| SCHEMBL367679 | 0.79 | — | — | |
| SCHEMBL4260594 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109666682-B | Rice serine hydroxymethyl transferase coding gene OsSHM4 mutant and application thereof | 南京农业大学 | 2022-03-04 | — | — | CN | claimed |
| CN-109666682-A | Rice serine hydroxymethyl transferase encoding gene OsSHM4 mutant and its application | 南京农业大学 | 2019-04-23 | — | — | CN | claimed |
| CN-107841549-A | Detection kit and determination method for methylation degree of serine hydroxymethyltransferase gene promoter region | 深圳市南山区慢性病防治院 | 2018-03-27 | — | — | CN | claimed |
| CN-107586797-A | The method that one pot of enzyme process prepares levodopa | 长兴制药股份有限公司 | 2018-01-16 | — | — | CN | claimed |
| CN-104774866-B | The double expression application of arabidopsis serine hydroxymethylase gene and formate dehydrogenase gene | 昆明理工大学 | 2017-11-10 | — | — | CN | claimed |
| CN-106536724-A | Method for producing l-amino acids in corynebacteria by using glycine cleavage system | 赢创德固赛有限公司 | 2017-03-22 | — | — | CN | claimed |
| EP-3090070-A1 | COMPOSITIONS AND METHODS FOR BIOLOGICAL PRODUCTION OF AMINO ACIDS IN HYDROGENOTROPHIC MICROORGANISMS | Trelys, Inc. (US) | 2016-11-09 | — | — | EP | claimed |
| CN-105861534-A | Biological method for improving yield of L-5-methyltetrahydrofolate by virtue of two-plasmid engineering bacteria | 中国药科大学 | 2016-08-17 | — | — | CN | claimed |
| WO-2015103497-A1 | COMPOSITIONS AND METHODS FOR BIOLOGICAL PRODUCTION OF AMINO ACIDS IN HYDROGENOTROPHIC MICROORGANISMS | TRELYS, INC. (US) | 2015-07-09 | — | — | WO | claimed |
| CN-104718292-A | Microorganism having carbon dioxide fixation cycle introduced thereinto | MITSUI CHEMICALS INC | 2015-06-17 | — | — | CN | claimed |
| CN-1989252-A | Microorganisms for producing sulfur-containing compounds | BASF AG (DE) | 2007-06-27 | — | — | CN | claimed |
| CN-1989247-A | P2－10Expression unit | BASF AG (DE) | 2007-06-27 | — | — | CN | claimed |
| CN-1989243-A | P180Expression unit | BASF AG (DE) | 2007-06-27 | — | — | CN | claimed |
| CN-1984991-A | P1-35 expression units | BASF AG (DE) | 2007-06-20 | — | — | CN | claimed |
| CN-1934265-A | Process for the production of l-amino acids using coryneform bacteria | DEGUSSA (DE) | 2007-03-21 | — | — | CN | claimed |
| CN-1898388-A | PGRO expression unit | BASF AG (DE) | 2007-01-17 | — | — | CN | claimed |
| CN-1894411-A | PSOD expression unit | BASF AG (DE) | 2007-01-10 | — | — | CN | claimed |
| CN-1894412-A | PEF-TU expression units | BASF AG (DE) | 2007-01-10 | — | — | CN | claimed |
| CN-1656229-A | Method for producing sulfur-containing fine chemicals by fermentation | BASF AG (DE) | 2005-08-17 | — | — | CN | claimed |
| CN-1225944-A | Unicellular or multicellular organisms for preparing riboflavin | FORSCHUNGSZENTRUM JUELICH GMBH (DE) | 1999-08-18 | — | — | CN | claimed |