⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366162 | 1.00 | — | — | |
| SCHEMBL818996 | 1.00 | — | — | |
| Water SCHEMBL5917424 | 0.98 | ALOX15 (0.44) | — | |
| Hydrochloric Acid SCHEMBL1553115 | 0.98 | ALOX15 (0.44) | — | |
| SCHEMBL31615213 | 0.98 | ALOX15 (0.44) | — | |
| Hydrochloric Acid SCHEMBL593290 | 0.98 | ALOX15 (0.44) | — | |
| Hydrochloric Acid SCHEMBL4534897 | 0.98 | ALOX15 (0.44) | — | |
| Hydrochloric Acid SCHEMBL459507 | 0.98 | ALOX15 (0.44) | — | |
| Hydrochloric Acid SCHEMBL11223928 | 0.98 | ALOX15 (0.44) | — | |
| Hydrochloric Acid SCHEMBL16223251 | 0.95 | ALOX15 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678811-B | Asymmetric preparation method of florfenicol intermediate cyclic compound | 湖北中牧安达药业有限公司 | 2020-12-29 | — | — | CN | claimed |
| EP-3113778-B1 | PYRIDAZINE DERIVATIVES FOR USE IN THE PREVENTION OR TREATMENT OF AN ATAXIC DISORDER | TAKEDA PHARMACEUTICALS CO (JP) | 2018-06-06 | — | — | EP | claimed |
| US-20170014407-A1 | PYRIDAZINE DERIVATIVES FOR USE IN THE PREVENTON OR TREATMENT OF AN ATAXIC DISORDER | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-01-19 | — | — | US | claimed |
| EP-3113778-A1 | PYRIDAZINE DERIVATIVES FOR USE IN THE PREVENTION OR TREATMENT OF AN ATAXIC DISORDER | Takeda Pharmaceutical Company Limited (JP) | 2017-01-11 | — | — | EP | claimed |
| WO-2015132608-A1 | PYRIDAZINE DERIVATIVES FOR USE IN THE PREVENTION OR TREATMENT OF AN ATAXIC DISORDER | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-09-11 | — | — | WO | claimed |
| WO-2025123013-A1 | COMPOSITIONS FOR TREATING ADDICTION, DEPENDENCE, WITHDRAWAL, AND/OR OPIOID INDUCED HYPERALGESIA | CASE WESTERN RESERVE UNIVERSITY (US) | 2025-06-12 | — | — | WO | disclosed |
| WO-2025055882-A1 | MB-102 RELATED COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2025-03-20 | — | — | WO | disclosed |
| CN-118908922-A | Benzylphenyl ether compound containing benzofuran and benzothiophene, and preparation method and application thereof | 广西大学 | 2024-11-08 | — | — | CN | disclosed |
| CN-118265699-A | Asymmetric biphenyl derivative and preparation method and medical application thereof | 西安新通药物研究股份有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-115504973-B | Benzisoxazole compound, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-05-14 | — | — | CN | disclosed |
| WO-2024088036-A1 | ASYMMETRIC BIPHENYL DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 西安新通药物研究股份有限公司 | 2024-05-02 | — | — | WO | disclosed |
| CN-117769543-A | Method for preparing pyrazine carboxylic acid derivatives as fluorescent tracers | 杭州中美华东制药有限公司 | 2024-03-26 | — | — | CN | disclosed |
| EP-1084704-A1 | REMEDIES FOR SPINOCEREBELLAR ATAXIA AND COMPOSITIONS FOR TREATING SPINOCEREBELLAR ATAXIA | MEIJI SEIKA KAISHA LTD. (JP) | 2001-03-21 | — | — | EP | disclosed |
| WO-2000003739-A9 | (CAG)/Q EXPANSION DISORDERS | CORNELL RES FOUNDATION INC (US) | 2000-11-02 | — | — | WO | disclosed |
| EP-1015479-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-2000003739-A1 | (CAG)/Q EXPANSION DISORDERS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2000-01-27 | — | — | WO | disclosed |
| WO-1998046631-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| EP-0186292-B1 | TRIPEPTIDES AND SWEETENING AGENTS CONTAINING THE SAME | AJINOMOTO CO., INC. (JP) | 1990-05-16 | — | — | EP | disclosed |
| US-4780528-A | Tripeptides and sweetening agents containing the same | AJINOMOTO CO., INC. (JP) | 1988-10-25 | — | — | US | disclosed |
| EP-0186292-A2 | Tripeptides and sweetening agents containing the same | AJINOMOTO CO., INC. (JP) | 1986-07-02 | — | — | EP | disclosed |