Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.47 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 3/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745645 | 0.82 | TSHR (0.59) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL29751617 | 0.82 | TSHR (0.59) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL9788476 | 0.81 | ALDH1A1 (0.57) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL3612247 | 0.81 | TDP1 (0.54) | TDP1ALDH1A1TSHRCYP3A4CYP1A2 | |
| SCHEMBL1562229 | 0.81 | ALDH1A1 (0.49) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL11305698 | 0.81 | TSHR (0.49) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL12879284 | 0.81 | ALDH1A1 (0.47) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL27722915 | 0.81 | ALDH1A1 (0.41) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL16636956 | 0.79 | CYP1A2 (0.47) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL11326702 | 0.79 | MAPT (0.49) | TDP1ALDH1A1TSHRCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5600036-A | 2-trifluoromethyl-4-chlorobenzalchloride and 2-methyl-3-nitro-5-chlorobenzotrifluoride useful as intermediates for preparing 2-methyl-3-aminobenzotrifluoride | CENTRAL GLASS COMPANY, LIMITED (JP) | 1997-02-04 | — | — | US | claimed |
| US-5600036-A | 2-trifluoromethyl-4-chlorobenzalchloride and 2-methyl-3-nitro-5-chlorobenzotrifluoride useful as intermediates for preparing 2-methyl-3-aminobenzotrifluoride | CENTRAL GLASS COMPANY, LIMITED (JP) | 1997-02-04 | — | — | US | disclosed |
| US-5600036-A | 2-trifluoromethyl-4-chlorobenzalchloride and 2-methyl-3-nitro-5-chlorobenzotrifluoride useful as intermediates for preparing 2-methyl-3-aminobenzotrifluoride | CENTRAL GLASS COMPANY, LIMITED (JP) | 1997-02-04 | — | — | US | disclosed |
| US-5600036-A | 2-trifluoromethyl-4-chlorobenzalchloride and 2-methyl-3-nitro-5-chlorobenzotrifluoride useful as intermediates for preparing 2-methyl-3-aminobenzotrifluoride | CENTRAL GLASS COMPANY, LIMITED (JP) | 1997-02-04 | — | — | US | disclosed |
| US-5449831-A | Process of preparing 2-methyl-3-aminobenzotrifluoride | CENTRAL GLASS COMPANY, LIMITED (JP) | 1995-09-12 | — | — | US | disclosed |