Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 7/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915820 | 0.90 | ALDH1A1 (0.46) | MCHR1ALDH1A1L3MBTL1BPTFKDM4E | |
| SCHEMBL8916698 | 0.78 | BPTF (0.39) | ALDH1A1L3MBTL1BPTFKDM4EHPGD | |
| SCHEMBL8916463 | 0.76 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1BPTFKDM4EHPGD | |
| SCHEMBL8917672 | 0.74 | MCHR1 (0.62) | MCHR1NOTUM | |
| SCHEMBL8916936 | 0.73 | BPTF (0.46) | ALDH1A1L3MBTL1BPTFKDM4EHPGD | |
| SCHEMBL8916773 | 0.72 | BPTF (0.45) | ALDH1A1L3MBTL1BPTFKDM4EHPGD | |
| SCHEMBL8917878 | 0.72 | MCHR1 (0.62) | MCHR1ALDH1A1L3MBTL1BPTFHPGD | |
| SCHEMBL8917300 | 0.71 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1BPTFKDM4EHPGD | |
| SCHEMBL8915764 | 0.69 | BPTF (0.48) | ALDH1A1L3MBTL1BPTFKDM4EHPGD | |
| SCHEMBL8917714 | 0.68 | MCHR1 (0.55) | MCHR1ALDH1A1KDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0596125-A1 | CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |