SCHEMBL8916104

SCHEMBL8916104

CCOC(=O)/C=C\C(=O)Oc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.60
LMNA P02545 4/20 0.60
ALDH1A1 P00352 3/20 0.60
THRB P10828 1/20 0.60
HCAR2 Q8TDS4 2/20 0.57
MDM2 Q00987 2/20 0.54
MDM4 O15151 1/20 0.54
ZDHHC2 Q9UIJ5 1/20 0.54
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PTGS2 P35354 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8916114 1.00 MAPT (0.60) MAPTLMNAALDH1A1THRBHCAR2
Ether SCHEMBL10778923 0.87 ZDHHC2 (0.55) MAPTLMNAALDH1A1THRBHCAR2
SCHEMBL29031678 0.86 HCAR2 (0.59) MAPTLMNAALDH1A1THRBHCAR2
SCHEMBL356193 0.84 HPGD (0.57) MAPTHCAR2ZDHHC2MEN1KMT2A
SCHEMBL1249384 0.84 HPGD (0.57) MAPTHCAR2ZDHHC2MEN1KMT2A
SCHEMBL356194 0.84 HPGD (0.57) MAPTHCAR2ZDHHC2MEN1KMT2A
SCHEMBL6554226 0.83 MAPT (0.49) MAPTLMNAALDH1A1THRBHCAR2
SCHEMBL6554220 0.83 MAPT (0.49) MAPTLMNAALDH1A1THRBHCAR2
SCHEMBL18355438 0.82 MAPT (0.51) MAPTLMNAALDH1A1THRBHCAR2
SCHEMBL4647853 0.82 MAPT (0.48) MAPTLMNAALDH1A1THRBHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119931726-A Smoke-reducing fuel composition and application thereof 中国石油化工股份有限公司 2025-05-06 CN disclosed
CN-119931727-A Fuel composition and application thereof 中国石油化工股份有限公司 2025-05-06 CN disclosed
CN-115141663-B Additive for improving lubricating property of gasoline and gasoline composition 中国石油化工股份有限公司 2023-12-12 CN disclosed
CN-115537242-B Diesel antiwear agent composition, preparation method thereof and diesel oil composition 中国石油化工股份有限公司 2023-11-10 CN disclosed
CN-113462443-B Diesel antiwear agent composition, preparation method thereof and diesel oil composition 中国石油化工股份有限公司 2023-07-14 CN disclosed
CN-115537242-A Diesel antiwear agent composition, preparation method thereof and diesel composition 中国石油化工股份有限公司 2022-12-30 CN disclosed
CN-113462443-A Diesel antiwear agent composition, preparation method thereof and diesel composition 中国石油化工股份有限公司 2021-10-01 CN disclosed
US-5663229-A Ternary polymer mixture and its use EMS-INVENTA AG (CH) 1997-09-02 US disclosed