SCHEMBL6554226

SCHEMBL6554226

CCOC(=O)C=CC(=O)OC(Br)C(=O)Oc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.49
LMNA P02545 4/20 0.49
ALDH1A1 P00352 3/20 0.49
THRB P10828 1/20 0.49
MDM2 Q00987 2/20 0.47
MDM4 O15151 1/20 0.47
HCAR2 Q8TDS4 2/20 0.44
ZDHHC2 Q9UIJ5 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
ATM Q13315 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6554220 1.00 MAPT (0.49) MAPTLMNAALDH1A1THRBMDM2
SCHEMBL8916104 0.83 MAPT (0.60) MAPTLMNAALDH1A1THRBMDM2
SCHEMBL8916114 0.83 MAPT (0.60) MAPTLMNAALDH1A1THRBMDM2
SCHEMBL6556011 0.81 MAPT (0.50) MAPTLMNAALDH1A1THRBMDM2
SCHEMBL6556004 0.81 MAPT (0.50) MAPTLMNAALDH1A1THRBMDM2
SCHEMBL4647853 0.77 MAPT (0.48) MAPTLMNAALDH1A1THRBMDM2
SCHEMBL4643328 0.75 TDP1 (0.49) MAPTLMNAALDH1A1THRBMDM2
SCHEMBL4643553 0.74 MAOB (0.41) MAPTLMNAALDH1A1THRBMDM2
SCHEMBL4641916 0.74 MAOB (0.41) MAPTLMNAALDH1A1THRBMDM2
SCHEMBL4641899 0.74 MAOB (0.41) MAPTLMNAALDH1A1THRBMDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed