Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.58 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.58 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.58 |
| ▸ | ACP3 | P15309 | 1/20 | 0.56 |
| ▸ | FDFT1 | P37268 | 3/20 | 0.56 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LAP3 | P28838 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544118 | 0.90 | FDFT1 (0.71) | ANPEPERAP1ERAP2ACP3FDFT1 | |
| SCHEMBL9632621 | 0.85 | FDFT1 (0.54) | ANPEPERAP1ERAP2ACP3FDFT1 | |
| SCHEMBL7605703 | 0.83 | ANPEP (0.56) | ANPEPERAP1ERAP2ACP3FDFT1 | |
| SCHEMBL10711154 | 0.81 | ANPEP (0.54) | ANPEPERAP1ERAP2ACP3FDFT1 | |
| SCHEMBL9632927 | 0.81 | FDPS (0.57) | FDFT1S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL9662849 | 0.81 | FDPS (0.62) | FDFT1S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL10106389 | 0.81 | FDFT1 (0.64) | ANPEPERAP1ERAP2ACP3FDFT1 | |
| SCHEMBL9165792 | 0.79 | ANPEP (0.51) | ANPEPERAP1ERAP2ACP3FDFT1 | |
| SCHEMBL9634062 | 0.79 | FDPS (0.44) | FDFT1S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL17475095 | 0.79 | ANPEP (0.47) | ANPEPERAP1ERAP2ACP3S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4371527-A | CIRCULATING HIGH DENSITY LIPOPROTEINS AND CLEARING CHOLESTEROL | SYMPHAR S.A. (CH) | 1983-02-01 | — | — | US | claimed |
| EP-0015370-B1 | DIPHOSPHONATE OR PHOSPHATE-PHOSPHONATE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1983-01-12 | — | — | EP | claimed |
| EP-0015370-A1 | Diphosphonate or phosphate-phosphonate derivatives and pharmaceutical compositions containing them | SYMPHAR S.A. (CH) | 1980-09-17 | — | — | EP | claimed |
| US-5624917-A | Method of inhibiting squalene synthetase | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0541037-A2 | Squalene synthetase inhibitory composition and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-05-12 | — | — | EP | disclosed |
| US-4416877-A | Anti-atherosclerotic pharmaceutical compositions containing diphosphonate compounds | SYMPHAR S.A. (CH) | 1983-11-22 | — | — | US | disclosed |
| US-4371527-A | CIRCULATING HIGH DENSITY LIPOPROTEINS AND CLEARING CHOLESTEROL | SYMPHAR S.A. (CH) | 1983-02-01 | — | — | US | disclosed |
| EP-0015370-B1 | DIPHOSPHONATE OR PHOSPHATE-PHOSPHONATE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1983-01-12 | — | — | EP | disclosed |
| US-4309364-A | Diphosphonates | SYMPHAR S.A. (CH) | 1982-01-05 | — | — | US | disclosed |
| EP-0015370-A1 | Diphosphonate or phosphate-phosphonate derivatives and pharmaceutical compositions containing them | SYMPHAR S.A. (CH) | 1980-09-17 | — | — | EP | disclosed |