Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 0.52 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.52 |
| ▸ | FNTB | P49356 | 7/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916478 | 0.91 | FNTA (0.51) | FNTAPGGT1BFNTB | |
| SCHEMBL8915375 | 0.88 | FNTA (0.62) | FNTAPGGT1BFNTB | |
| SCHEMBL9129439 | 0.73 | FNTA (0.49) | FNTAPGGT1BFNTB | |
| SCHEMBL9574954 | 0.73 | FNTA (0.52) | FNTAPGGT1BFNTB | |
| SCHEMBL31310901 | 0.71 | KMT2A (0.53) | FNTAPGGT1BFNTB | |
| SCHEMBL9127713 | 0.71 | FNTA (0.50) | FNTAPGGT1BFNTB | |
| SCHEMBL8620653 | 0.71 | — | — | |
| SCHEMBL6551480 | 0.71 | FNTA (0.70) | FNTAPGGT1BFNTB | |
| SCHEMBL8620647 | 0.71 | — | — | |
| SCHEMBL6550133 | 0.70 | FNTA (0.59) | FNTAPGGT1BFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624917-A | Method of inhibiting squalene synthetase | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0541037-A2 | Squalene synthetase inhibitory composition and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-05-12 | — | — | EP | disclosed |