Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.62 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.62 |
| ▸ | FNTB | P49356 | 4/20 | 0.61 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916369 | 0.88 | FNTA (0.52) | FNTAPGGT1BFNTB | |
| SCHEMBL8916478 | 0.87 | FNTA (0.51) | FNTAPGGT1BFNTB | |
| SCHEMBL9473523 | 0.80 | FNTA (0.61) | FNTAPGGT1BFNTBGGPS1 | |
| SCHEMBL9473534 | 0.80 | FNTA (0.61) | FNTAPGGT1BFNTBGGPS1 | |
| SCHEMBL9574954 | 0.80 | FNTA (0.52) | FNTAPGGT1BFNTB | |
| SCHEMBL8940569 | 0.79 | FNTA (0.67) | FNTAPGGT1BFNTBGGPS1 | |
| Phosphoric Acid SCHEMBL2970524 | 0.78 | KMT2A (0.64) | FNTAFNTBGGPS1 | |
| SCHEMBL4461665 | 0.78 | KMT2A (0.64) | FNTAPGGT1BFNTBGGPS1 | |
| Phosphoric Acid SCHEMBL18042462 | 0.78 | KMT2A (0.64) | FNTAFNTBGGPS1 | |
| Phosphoric Acid SCHEMBL16655450 | 0.78 | KMT2A (0.64) | FNTAFNTBGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624917-A | Method of inhibiting squalene synthetase | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0541037-A2 | Squalene synthetase inhibitory composition and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-05-12 | — | — | EP | disclosed |