Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 16/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915863 | 0.97 | TSHR (0.42) | TSHRGLANPSR1EGLN2PDE2A | |
| SCHEMBL4819318 | 0.90 | PDE2A (0.43) | TSHRGLANPSR1EGLN2PDE2A | |
| SCHEMBL8911798 | 0.90 | GLA (0.42) | TSHRGLANPSR1EGLN2PDE2A | |
| SCHEMBL8912954 | 0.87 | PDE2A (0.43) | TSHRGLANPSR1EGLN2PDE2A | |
| SCHEMBL8919073 | 0.87 | PDE2A (0.41) | TSHRGLANPSR1EGLN2PDE2A | |
| SCHEMBL7493479 | 0.84 | EGLN2 (0.43) | TSHRGLANPSR1EGLN2PDE2A | |
| SCHEMBL4819706 | 0.84 | PDE2A (0.40) | TSHRGLANPSR1EGLN2PDE2A | |
| SCHEMBL5593283 | 0.84 | PDE2A (0.40) | EGLN2PDE2A | |
| SCHEMBL4812000 | 0.83 | EGLN2 (0.45) | TSHREGLN2PDE2AALDH1A1LMNA | |
| SCHEMBL5593335 | 0.82 | PDE2A (0.39) | EGLN2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593996-A | FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1997-01-14 | — | — | US | disclosed |